CAMPBELL BIOLOGY IN FOCUS-MOD.MASTERING
CAMPBELL BIOLOGY IN FOCUS-MOD.MASTERING
3rd Edition
ISBN: 9780135191811
Author: Urry
Publisher: PEARSON
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Chapter 15.4, Problem 2CC

WHAT IF? Study the microarray in Figure 15.17. If a sample from normal tissue is labeled with a green fluorescent dye, and a sample from ca1cerous tissue is labeled red, what color spots would represent genes that you would be interested in if you were studying cancer? Explain.

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3. Figure on the right shows a DNA Genes expressed microarray assay of gene in cancerous expression levels. In this tissue: Red microarray if a sample with normal tissue is labeled with Genes expressed in normal tissue: green fluorescent dye, and a Green sample with cancerous tissue is labeled with red, what colored Genes expressed in both tissues: spots would represent genes that you would be interested in if you Yellow were studying cancer? Explain. Genes expressed in neither tissue: Black
GENETICS QUESTION!! Imagine that you are a geneticist at a hospital and you are given a file for a patient whose family has a history of cancer. The patient, John Doe, is 18 years old and has had a biopsy done on a tumorous growth in his adrenal gland. He has a sister, Jane, and a brother, Bob, who are younger than he is and who are both healthy. His mother, Betty, has a diagnosis of breast cancer. John’s father, Joe, and John’s paternal grandparents have no history of cancer. Betty is one of four children. Her brother, Tom, and sister, Lucy, have never had cancer or signs of cancer. Both Tom and Lucy are older than Betty. Betty had another brother, Jake, who died very young of leukaemia. Tom has monozygotic twin daughters who are healthy. Betty’s father, Don, died of soft tissue sarcoma in his thirties. Betty’s mother is alive and healthy. Betty’s paternal grandmother, Don’s mother, died of a brain tumor in her thirties. Don had no siblings. As part of your research, you also consult…
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