Concept explainers
To explain: How the activity of the citrate synthase is regulated by succinyl CoA, on the basis of the graph given.
Introduction:
Citrate synthase is found in almost all the living cells. This enzyme functions as the catalyst in the citric acid cycle. Citric acid is found in mitochondrial matrix of eukaryotic cells but it is not encoded by mitochondrial DNA instead it is encoded by nuclear DNA. Succinyl CoA resembles acetyl CoA in structure and it inhibits the activity of the enzyme citric acid synthase.
To explain: Why succinyl CoA is a suitable indicator for the regulation of citric acid cycle.
Introduction:
Succinyl CoA is a competitive inhibitor of acetyl CoA. Acetyl CoA is responsible for the activity of the enzyme citrate synthase. Increased concentration of succinyl CoA decreases the amount of acetyl CoA, hence activity of citrate synthase is regulated.
To explain: How the rate of
Introduction:
Citric acid cycle is a type of cellular respiration which takes place in the mitochondrial matrix. Citric acid cycle is an aerobic cellular respiration which requires oxygen for proper functioning.
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