Concept explainers
To determine: The reaction involved in the conversion of isocitrate into α- ketoglutarate.
Introduction:
Citric acid cycle is a chain of
To determine: The role of cofactor in the
Introduction:
Every enzyme present in the cell catalyzes the reactions of the cell. There is a non protein part that is associated with the enzyme, which is called a cofactor or prosthetic group. These cofactors are responsible for the proper functioning of the enzymes. Enzyme cannot perform in the absence of cofactors.
To determine: Similar reactions of citric acid cycle with the conversion of isocitrate into α- ketoglutarate.
Introduction:
Conversion of isocitrate into α- ketoglutarate is a decarboxylation process and it occurs in the presence of the enzyme isocitrate dehydrogenase. This enzyme reduces isocitrate to yield α- ketoglutarate. This reaction is the third step of the citric acid cycle, the similar reactions may take place in the whole cycle.
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Lehninger Principles of Biochemistry
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