Microbiology: A Systems Approach
5th Edition
ISBN: 9781259706615
Author: Marjorie Kelly Cowan Professor
Publisher: McGraw-Hill Education
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Chapter 16, Problem 8MCQ
Summary Introduction
Introduction:
An autoantibody is a type of protein or antibody produced by the immune system that acts against one or more of the individual's own proteins. Most of the autoimmune diseases are caused by such auto-antibodies.
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Activated helper T Cells participate in which of the following processes?
a.) Differentiation of memory B cells
b.) Activation of cytotoxic T Cells
c.) Facilitation of macrophage phagocytosis
d.) All of above
Explain each of the ways that the immune system has a mechanism of control in the development and function of B cells.
What are the ramifications if these control mechanisms are not in place?
What control mechanism do you feel is the most important to the development and function of B cells?
There are different pathways through which B cells can be activated, one of which is CD4 T - independent cells, in which the antigen is large and has repeating patterns that make crosslinking and activation of several BCRs at the same time.
A.true
B.false
Chapter 16 Solutions
Microbiology: A Systems Approach
Ch. 16.1 - Define immunopathology, and describe the two major...Ch. 16.1 - Prob. 2AYPCh. 16.2 - Prob. 3AYPCh. 16.2 - Outline the steps of a type I allergic response,...Ch. 16.2 - Identify three conditions caused by IgE-mediated...Ch. 16.2 - Prob. 6AYPCh. 16.2 - Prob. 7AYPCh. 16.2 - Prob. 8AYPCh. 16.3 - List the three immune components causing cell...Ch. 16.3 - Prob. 10AYP
Ch. 16.3 - Prob. 11AYPCh. 16.4 - Prob. 12AYPCh. 16.4 - Prob. 13AYPCh. 16.5 - Prob. 14AYPCh. 16.5 - List four classes of grafts, and explain how host...Ch. 16.6 - Prob. 16AYPCh. 16.6 - Prob. 17AYPCh. 16.7 - Prob. 18AYPCh. 16.7 - Prob. 19AYPCh. 16.7 - Prob. 20AYPCh. 16 - Prob. 1MCQCh. 16 - Prob. 2MCQCh. 16 - The contact with allergen that results in symptoms...Ch. 16 - Prob. 4MCQCh. 16 - Prob. 5MCQCh. 16 - Prob. 6MCQCh. 16 - Prob. 7MCQCh. 16 - Prob. 8MCQCh. 16 - Prob. 9MCQCh. 16 - Prob. 10MCQCh. 16 - Prob. 11TFCh. 16 - Prob. 12TFCh. 16 - Prob. 13TFCh. 16 - Prob. 14TFCh. 16 - Prob. 15TFCh. 16 - Prob. 1CTQCh. 16 - Summarize the roles of the microbiome and genetics...Ch. 16 - Prob. 3CTQCh. 16 - Prob. 4CTQCh. 16 - Prob. 5CTQCh. 16 - From chapter 15. figure 15.1. How would a persons...Ch. 16 - Prob. 2VCCh. 16 - Prob. 1CM
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- B lymphocytes, the precursors of plasma cells, are triggered to proliferate by the binding of multivalent antigens to receptors on their surfaces. The cell-surface receptors are transmembrane immunoglobulins. Univalent antigens, in contrast, do not activate B cells. (a) What do these findings reveal about the mechanism of B-cell activation? (b) How might antibodies be used to activate B cells?arrow_forwardWhich of these statements about the Fab portion of antibodies is true? a.It binds to antigens. b.Its amino acid sequences are variable. c. It consists of both H and L chains. d. All of these are true.arrow_forwardMark the following statements as true or false. If a statement is false, correct is to make a true statement. a. In the primary immune response, the lag phase lasts about 5 days, during which time B cells proliferate and differentiate. b. The secondary immune response is mediated by plasma cells. c. Subunit vaccines consist of pathogens that are alive but unable to cause disease. d. Vaccinations are given to induce the production of the inflammatory responsearrow_forward
- of the choices, which cells stimulate directly B cells to divide and produce antibodies? a. mast cells b. marcophages c. Nk cells d. TH cellsarrow_forwardIn the secondary response, the IgG levels rise much faster than they did during the first antibody response. Why is this?Choose one: A. The plasma cells that were produced for the first response have a very long half-life, so they are able to produce antibodies for the second response without activation of other B cells. B. Memory B cells are capable of producing antibodies directly, so there is no need to spend time differentiating them into plasma cells. C. By the secondary response, there are B cells and T cells that have differentiated into plasma cells, giving more total plasma cells to work with. D. Memory B cells are present for the secondary response. Those cells are much easier to activate than the naive B cells; therefore, the response occurs much more quickly and on a larger scale.arrow_forwardWhich statement describes a limitation of T-cell receptors (TCRs) compared to B-cell receptors (BCRs)? A.) only BCRs can interact with epitopes on free antigens or epitopes B.) displayed directly on the pathogen C.) only BCRs can initiate a pathogen-specific immune response D.) only BCRs recognize pathogen epitopesarrow_forward
- Natural killer cellsa. are known for attacking large parasites, such as tapeworms.b. engulf pathogens and present antigens to T cells.c. recognize the absence of MHC-I molecules on a cell surface.d. produce antibodies.arrow_forwardFor question with blanks, choose the combination of answers that most accurately completes the statement. In humans, B cells mature in the .................. and T cells mature in the . a. GALT, liver b. bursa, thymus c. bone marrow, thymus d. lymph nodes, spleenarrow_forwardWhich of the following statements regarding T cells activated by specific antigen is incorrect? a. They receive co-stimulatory signals through CD28. b. They suppress expression of sphingosine 1-phosphate (SIP). c. They take several days before differentiating into effector T cells. d. They cease to secrete and respond to interleukin-2 (IL-2). e. They begin to express CTLA4, which serves to limit T-cell proliferation.arrow_forward
- DiGeorge syndrome is a congenital disease that results in a poorly developed, nonfunctioning thymus gland. Which of the following would be a likely problem experienced by a baby with DiGeorge syndrome? a. lack of B cells b. lack of antibodies c. lack of T cells d. lack of macrophagesarrow_forwardAn allergy can best be defined as ______. A) a component of the humoral response B) an exaggerated response to an allergen C) part of the normal immune response D) a type of cell-mediated adaptive immunityarrow_forwardExplain why each choice (a-d) is correct or incorrect. A vaccine is effective because a. The vaccine contains the antibodies necessary to fight infection. b. The vaccine contains the lymphocytes necessary to fight infection. c. The secondary response of the adaptive immunity is faster and more efficient than the primary response. d. B lymphocytes are unable to mount an immune response the first time they are exposed to a new pathogen.arrow_forward
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