Biology: The Dynamic Science (MindTap Course List)
Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN: 9781305389892
Author: Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher: Cengage Learning
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Chapter 16, Problem 8TYK
Summary Introduction

Introduction:

Every organism has a definite body pattern. There are two classes of genes, namely, housekeeping genes and expression genes, which control the development of body parts of an organism. These are maternal effect genes and segmentation genes. These genes encode proteins that regulate the gene expression.

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Another way to study the role of proteins (e.g., transcription factors) that function in development is to microinject the mRNA that encodes a protein, or the purified protein itself, into an oocyte or embryo, and then determine how this affects the subsequent development of the embryo, larva, and adult. For example, if Bicoid protein is injected into the posterior region of an oocyte, the resulting embryo will develop into a larva that has anterior structures at both ends. Based on your understanding of the function of each developmental gene, what would be the predicted phenotype if the following proteins or mRNAs were injected into normal oocytes? A. Nanos mRNA injected into the anterior end of an oocyte B. Antp protein injected into the posterior end of an embryo C. Toll mRNA injected into the dorsal side of an early embryo
You found a strain of mutant fruit flies (Drosophila) living on the rotten bananas in your dorm room. You notice that many of the larvae have abnormal abdominal segments. You want to know if the “abdomenless” mutation is a maternal effect gene. Describe an experiment you would do to determine this, and the results that would support and contradict the notion that the abdomenless gene encodes a maternal determinant.
Developmental genes are often highly conserved. However, organisms with very similar genes can appear quite different. How is this possible? A. The genes may usually undergo mutation during development, resulting in the production of varied proteins in individual cells. B. If an identical gene is turned on at different stages in development, it can have very different effects. C. Even if genes are quite similar, they always produce proteins with different functions. D. If the genes are very similar, they must always be expressed similarly (at similar times in development) but may sometimes still have varying effects.
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