Life: The Science of Biology
11th Edition
ISBN: 9781319010164
Author: David E. Sadava, David M. Hillis, H. Craig Heller, Sally D. Hacker
Publisher: W. H. Freeman
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Chapter 16.3, Problem 1R
Summary Introduction
To review:
The negative and positive gene expression regulation in the life cycles of bacteriophage λ and the HIV (human immune deficiency virus).
Introduction:
An activator binds to a specific site on a DNA (deoxyribonucleic acid) sequence near the promoter or far away from the promoter and initiates transcription. This is positive regulation of the gene transcription. In the case of negative regulation, a repressor protein binds to the promoter and prevents the process of transcription. Bacteriophage λ and HIV show both positive and negative regulation of gene expression.
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Life: The Science of Biology
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- Describe the stages in the multiplication cycle of bacteriophages.arrow_forwardBriefly describe the role of the Lambda repressor (cI) and cII activator to regulate the switch betweenthe lytic and lysogenic cycles of phage Lambda.arrow_forwardWhich form of HIV RNA, fully spliced, incompletely spiced, or unspliced, is needed during the early stage of the synthesis of HIV components?arrow_forward
- The RNA transcript of a region of T4 phage DNA contains the sequence 5’-AAAUGAGGA-3'. This sequence encodes three different polypeptides. What are they?arrow_forwardDiscuss the lysogrnic induction of bacteriophage lambda in coli cellsarrow_forwardAfter lambda infects a cell, how does it decide to create a lysogen? Name the major cis and transplayers and their function.arrow_forward
- Discuss the following: Lysogeny establishment in bacteriophage lambda Lysogeny mentainance in bacteriophage lambda Antitermination in bacteriophage lambda Retroregulation in bacteriophage lambda The process of induction in bacteriophage lambdaarrow_forwardDescribe the role that integrase plays during the insertion of λDNA into the host chromosome.arrow_forwardDescribe in general terms how bacteriophage lambda regulates the switch between lytic and lysogenic cyclesarrow_forward
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