BIOCHEMISTRY (LOOSELEAF)-W/ACCESS
9th Edition
ISBN: 9781319425784
Author: BERG
Publisher: Macmillan Higher Education
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Question
Chapter 17, Problem 9P
Interpretation Introduction
Interpretation:
Difference between the catalytic and stoichiometric coenzymes in the pyruvate dehydrogenase complex.
Concept introduction:
Pyruvate dehydrogenase enzyme complex is required for the linking of glycolysis and TCA. The five enzymes which form the pyruvate dehydrogenase complex are pyruvate dehydrogenase, dihydrolipoyl dehydrogenase, Kinase, dihydrolipoyl transacetylase, and phosphatase. It helps in the conversion of pyruvate into Acetyl CoA. Acetyl CoA then enters into the series of the citric acid cycle.
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Students have asked these similar questions
Closely related. Pyruvate dehydrogenase complex and a-ketoglutarate
a-ketoglutarate dehydrogenase complex are huge enzymes
consisting of three discrete enzymatic activities. Which amino acids
require a related enzyme complex, and what is the name of the
enzyme?
G. ENZYME CLASSIFICATION.
Identify the main class of enzymes used to catalyzed the following reactions:
1. Lactate dehydrogenase:
NADH+H
NAD
HC-OH
CH3
CH
Pynnte
Lactate
2. Methylmalonyl-CoA mutase:
CH CH
SCOA
CH,CH,
SCOA
coenzyme B12
COO
COO
methylmalonyl-CoA
succinyl-CoA
3. Enolase:
0.
H–Ċ–0–P–0-
C-0–P-0- + H,0
HO–CH,
CH 6
Phosphoenolpyruvate
2-Phosphoglycerate
4. Chymotrypsin:
-0–CH,CH3 + H2O
- RCOOH + HOCH,CH3
5. Pyruvate carboxylase:
coo
• co, • ATP + H,0
H-C-H . ADP + P, + 2H
čoo
CH,
Pyruvate
Oxaleacetate
Long explanations are NOT NEEDED. Answer only d and e.
ATP accounting.
Consider 1 molecule of the sucrose (monomeric units: glucose and fructose) that will undergo complete oxidation.
-Number of pyruvate molecules after glycolysis is 4.-Net ATP produced in glycolysis only (via substrate-level phosphorylation) is 2.-Number of NADH produced using the pyruvate dehydrogenase complex reaction is 1.
Now find:d. Number of NADH and FADH2 produced from Krebs cycle.e. Net ATP produced (complete oxidation via Malate aspartate shuttle).
Chapter 17 Solutions
BIOCHEMISTRY (LOOSELEAF)-W/ACCESS
Ch. 17 - Prob. 1PCh. 17 - Prob. 2PCh. 17 - Prob. 3PCh. 17 - Prob. 4PCh. 17 - Prob. 5PCh. 17 - Prob. 6PCh. 17 - Prob. 7PCh. 17 - Prob. 8PCh. 17 - Prob. 9PCh. 17 - Prob. 10P
Ch. 17 - Prob. 11PCh. 17 - Prob. 12PCh. 17 - Prob. 13PCh. 17 - Prob. 14PCh. 17 - Prob. 15PCh. 17 - Prob. 16PCh. 17 - Prob. 17PCh. 17 - Prob. 18PCh. 17 - Prob. 19PCh. 17 - Prob. 20PCh. 17 - Prob. 21PCh. 17 - Prob. 22PCh. 17 - Prob. 23PCh. 17 - Prob. 24PCh. 17 - Prob. 25PCh. 17 - Prob. 26PCh. 17 - Prob. 27PCh. 17 - Prob. 28PCh. 17 - Prob. 29PCh. 17 - Prob. 30PCh. 17 - Prob. 31PCh. 17 - Prob. 32PCh. 17 - Prob. 33PCh. 17 - Prob. 34PCh. 17 - Prob. 35PCh. 17 - Prob. 36PCh. 17 - Prob. 37PCh. 17 - Prob. 38PCh. 17 - Prob. 39PCh. 17 - Prob. 40PCh. 17 - Prob. 41PCh. 17 - Prob. 42PCh. 17 - Prob. 43PCh. 17 - Prob. 44P
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Similar questions
- Long explanations are not needed. True or Falsea. One NADH is produced for every pyruvate molecule undergoing oxidation using the enzyme pyruvate dehydrogenase complex b. Erythrose-4-phosphate can be synthesized using the pentose phosphate pathway.arrow_forwardLong explanations are NOT NEEDED. I pretty much have an idea already about this lesson, I would just like to see if my answers are correct, if it's wrong then kindly correct and just add a short explanation. ATP accounting. Consider 1 molecule of the sucrose (monomeric units: glucose and fructose) that will undergo complete oxidation. a. Number of pyruvate molecules after glycolysis is 4.b. Net ATP produced in glycolysis only (via substrate-level phosphorylation) is 2.c. Number of NADH produced using the pyruvate dehydrogenase complex reaction is 1.d. Number of NADH and FADH2 produced from Krebs cycle is 12 and 4 respectively.e. Net ATP produced (complete oxidation via Malate aspartate shuttle) is 64.arrow_forwardButch Cassidy and the Sundance Kid. Glutamate dehydrogenase requires which of the following cofactors: a. NAD+/NADP+NAD*/NADP+ b. Pyridoxal phosphate c. Thiamine pyrophosphate d. Biopterinarrow_forward
- Long explanations are NOT NEEDED. ATP accounting. Consider 1 molecule of the sucrose (monomeric units: glucose and fructose) that will undergo complete oxidation. a. Number of pyruvate molecules after glycolysis.b. Net ATP produced in glycolysis only (via substrate-level phosphorylation).c. Number of NADH produced using the pyruvate dehydrogenase complex reaction.d. Number of NADH and FADH2 produced from Krebs cycle.e. Net ATP produced (complete oxidation via Malate aspartate shuttle).arrow_forward. Describe the reaction steps of the citric acid cycle with a focus on their control. In addition discuss the energy provided to a living cell from the metabolism of one acetyl-CoA entering the citric acid cyclearrow_forwardLong explanations are NOT NEEDED. ATP accounting. Consider 1 molecule of the sucrose (monomeric units: glucose and fructose) that will undergo complete oxidation. d. Number of NADH and FADH2 produced from Krebs cycle.e. Net ATP produced (complete oxidation via Malate aspartate shuttle).arrow_forward
- Draw Gluconeogenesis. Please make sure to state all the enzymes and co-factors for each step of the pathway.arrow_forwardDraw Glycolysis. Please make sure to state all the enzymes and co-factors for each step of the pathway.arrow_forwardBIOCHEMISTRY. Could glycerol be used to regenerate the OAA for maintenance of TCA cycle activity? Yes or No? Explain.arrow_forward
- The last stop. The final electron acceptor for the electron-transport chain is which of the following? do a. 0202 b. Coenzyme Q с. СО2СО, d. NAD+NAD+arrow_forward. Pyruvate can be processed under anaerobic conditions to ethanol (in yeast) or to lactate (in mammals), as shown. Explain the primary purpose of these reactions. Describe the major biochemical features of each reactionarrow_forwardThey are everywhere. What energetic barrier prevents glycolysis from simply running in reverse tosynthesis glucose? What is the energetic cost to overcome this barrier?arrow_forward
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