a) Bromobenzene, 2-bromopropane, bromoethane
Interpretation:
The compounds bromoethane, 2-bromopropane and bromobenzene are to be ranked in the order of their reactivity in Williamson synthesis.
Concept introduction:
In Williamson synthesis, the primary
To rank:
The compounds bromoethane, 2-bromopropane and bromobenzene in the order of their reactivity in Williamson synthesis.
b) Chloroethane, bromoethane, 1-Iodopropene
Interpretation:
The compounds chloroethane, bromoethane and 1-iodopropene are to be ranked in the order of their reactivity in Williamson synthesis.
Concept introduction:
In Williamson synthesis, te alkoxuide reacts with primary alkyl halides through a SN2 mechanism. The requirements are thus a backside attack, a stronger nucleophile and a better leaving group. Among the halides, iodine is better leaving than bromine which in turn is a better leaving than chlorine. Vinyl halides are less reactive than alkyl halides.
To rank:
The compounds chloroethane, bromoethane and 1-iodopropene in the order of their reactivity in Williamson synthesis.
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Chapter 18 Solutions
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