(a)
Interpretation:
The given synthetic conversion by adding an organolithium reagent to an acid is to be shown.
Concept introduction:
Organolithium reagents are used in the synthesis of
(b)
Interpretation:
The given synthetic conversion by adding an organolithium reagent to acid is to be shown.
Concept introduction:
Organolithium reagents are used in the synthesis of ketones from carboxylic acids. They are reactive towards carbonyls and attack the lithium salt of carboxylate anions to form dianion. Then protonation of dianion takes place in the presence of hydronium ion to give hydrate of ketone which quickly loses water to form the ketone as a product.
(c)
Interpretation:
The given synthetic conversion by adding an organolithium reagent to acid is to be shown.
Concept introduction:
Organolithium reagents are used in the synthesis of ketones from carboxylic acids. They are reactive towards carbonyls and attack the lithium salt of carboxylate anions to form dianion. Then protonation of dianion takes place in the presence of hydronium ion to give hydrate of ketone which quickly loses water to form the ketone as a product.
(d)
Interpretation:
The given synthetic conversion by adding an organolithium reagent to acid is to be shown.
Concept introduction:
Organolithium reagents are used in the synthesis of ketones from carboxylic acids. They are reactive towards carbonyls and attack the lithium salt of carboxylate anions to form dianion. Then protonation of dianion takes place in the presence of hydronium ion to give hydrate of ketone which quickly loses water to form the ketone as a product.
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Organic Chemistry (9th Edition)
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