Biological Science (7th Edition)
7th Edition
ISBN: 9780134678320
Author: Scott Freeman, Kim Quillin, Lizabeth Allison, Michael Black, Greg Podgorski, Emily Taylor, Jeff Carmichael
Publisher: PEARSON
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Chapter 19, Problem 4TYK
Summary Introduction
Introduction:
Splicing refers to the editing of the precursor mRNA (messenger ribonucleic acid) and to transcript it into mature messenger mRNA. The introns are removed and exons are ligated together, after the splicing process.
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Students have asked these similar questions
If an MRNA is alternatively spliced, then
different introns are removed from a pre-MRNA, producing transcripts that will potentially encode proteins with different primary structures.
I.
the MRNA is found in a bacterial cell.
II.
transcription and translation of the MRNA will occur simultaneously.
the alternative splicing happened in the cytoplasm.
IV.
Ay different exons from a pre-mRNA will be spliced together.
V.
the different MRNAS will all have poly-A tails.
VI.
Why might a single base-pair mutation in eukaryotic mRNA be less serious than one in prokaryotic mRNA?
a. If the mutation occurs in the 5' end of the start site, it will not affect the gene product.
b. If the mutation occurs in the exon, it will not affect the gene product.
c. If the mutation occurs in the splice site of a transcript with alternative splicing, only one gene product may
affected.
O d. If the mutation occurs in the intron or not in the splice site of a transcript with alternative splicing, it will nc
affect the gene product.
O e. If the mutation occurs in the 3' end of the start site, it will not affect the gene product.
OLIE STIC N 1A
Researchers are designing and testing antisense drugs as therapies for a variety of diseases, inclusing cancer, AIDS, diabeates, and muscular dystrophy. The drugs are also being tested to fight infection by deadly viruses such as Ebola. Antisense drugs consist of short RNA strands coplementary in sequence to mRNAs that form during the progression of a disease. How do you think these drugs work?
Chapter 19 Solutions
Biological Science (7th Edition)
Ch. 19 - What is chromatin? a. the histone-containing...Ch. 19 - Prob. 4TYKCh. 19 - Compare and contrast the items in each pair: (a)...Ch. 19 - Prob. 6TYUCh. 19 - Prob. 8TYUCh. 19 - Prob. 9TYPSSCh. 19 - 10. QUANTITATIVE Imagine repeating the experiment...Ch. 19 - Prob. 12PIATCh. 19 - Prob. 13PIATCh. 19 - Prob. 14PIAT
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- How would each of the following types of mutations affect proteinfunction or the amount of functional protein that is expressed froma gene?A. Nonsense mutationB. Missense mutationC. Up promoter mutationD. Mutation that affects splicingarrow_forwardArrange the statements in their proper order by writing the corresponding letter (e.g. A) for each statement in the space provided below. A. The single-stranded RNA would complement the target RNA. B. Gene expression is inactivated once the mRNA is no longer accessible for translation. C. The risk-induced silencing complex which is composed of RNA and protein subunits is formed. D. Double-stranded, non-coding RNA is cleaved by Dicer. E. The mRNA can be cleaved or remain bound by the RISC. 1. 2. 3. 4. 5.arrow_forwardAlternate splicing: A. Reduces mRNA half-life by shortening poly(A) tails B. Disrupts histone arrangement for increased transcription C. Uses topoisomerase to complete its function D. Can produce 2 or more products from one genearrow_forward
- What is the name of the process that adds a modified guanosine nucleotide to the 5’ phosphates of pre-mRNAs in eukaryotes? a. splicing b. polyadenylation c. capping d. nuclear export e. photophosphorylationarrow_forwardDuring RNA splicing a. All exons are removed and degraded in the cell b. mRNA is made from DNA template c. Introns are removed from the mRNA and the exons are spliced together d. mRNA is translated into a protein moleculearrow_forwardwhat is the first event to take place in translation in eukaryotic cell? a. An clongation of the polypeptide chain by the addition of amino acids b. Binding of the larger ribosomal subunits to the smaller ribosomal subunits c. Base pairing of activated methionine-tRNA to AUG of messenger RNA d. The small subunits of ribosome recognizing and attaching to 5' cap of mRNAarrow_forward
- What is the purpose of alternative splicing a. Alternative spiicing allows a protein to be included by multiple genes b. Alternative spicing allows for mutations to accumulate that won't affect the expression of a gene c. Alternative splicing allows for multiple mRNAs to be produced to ensure that the single proteins the gene and codes will be translated. d.arrow_forwardResearchers are designing and testing antisense drugs as therapies for a variety of diseases, including cancer, AIDS, diabetes, and muscular dystrophy. The drugs are also being tested to fight infection by deadly viruses such as Ebola. Antisense drugs consist of short RNA strands complementary in sequence to mRNAs that form during the progression of a disease. How do you think these drugs work?arrow_forwardWhich is the correct option here? How can one primary transcript result in several polypeptides with different amino acid sequences. A. Phosphorylation of proteins after translation B. alternative splicing of exons C. An addition of polyA tail to mRNA D. Incorporation of an amino acid at a stop codonarrow_forward
- What is one function of TFIIH during transcription? a. Recruiting the TATA-box binding protein to the TATA-box. b. Terminating transcription via factor-dependent termination. c. Capping the 5' end of mRNA with 7-methylguanylate. d. Phosphorylating the CTD of RNA polymerase.arrow_forwardHow does reverse methylation affect gene expression? Select one: o a. The gene is turned off, but still expresses a protein product. b. The gene becomes transcriptionally silent. c. There is no effect on the gene. d. The gene is hyperactive resulting in a gain of function. e. The gene expresses the wrong protein. Clear my choice How do microRNAs regulate epigenetic mechanisms during development? Select one: o a. MicroRNAs function as gene repressors b. You only find microRNAS in epigenetic and cancer cells c. MicroRNAs function as gene activators d. MicroRNAS regulate methylation on the DNA sequences of embryos e. Researchers find that when microRNAs are present the effects of epigenetic modifications are 50% greater Clear my choicearrow_forwardYou are studying how gene expression is regulated in the cell. For gene z, you find that while there are high levels of mRNA in the cell, there are low levels of the protein encoded by gene z. Describe a regulatory mechanism that could explain this finding that occurs after translation.arrow_forward
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