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Activated-protein-C (APC) resistance is a serum marker that has been associated with thrombosis (the formation of blood clots often leading to heart attacks) among adults. A study assessed this risk factor among adolescents. To assess the reproducibility of the assay, a split-sample technique was used in which a blood sample was provided by 10 people; each sample was split into two aliquots (sub-samples), and each aliquot was assessed separately. Table 2.19 gives the results.
Table 2.19 APC resistance split-samples data
To assess the variability of the assay, the investigators need to compute the coefficient of variation. Compute the coefficient of variation (CV) for each subject by obtaining the
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Chapter 2 Solutions
EBK FUNDAMENTALS OF BIOSTATISTICS
- A study was undertaken to investigate the effectiveness of an aquarobic exercise program for patients with osteoarthritis. A convenience sample of 70 individuals with arthritis was selected, and each person was randomly assigned to one of two groups. The first group participated in a weekly aquarobic exercise program for 8 weeks; the second group served as a control. Several pieces of data were collected from the individuals, including their total cholesterol (mg). Determine if there is a significant difference in the mean cholesterol for the two groups (aquarobic & control) at the start of the study using a significance level of 0.01. Difference Sample Diff. Std. Error df Aquarobic - Control -13.9045 6.8214 67.8635 What hypotheses should be tested? Make sure to select the hypotheses which are written with notation consistent with the type of samples selected. Ho:μd=0Ho:μd=0Ha:μd>0Ha:μd>0 Ho:μd=0Ho:μd=0Ha:μd<0Ha:μd<0 Ho:μ1=μ2Ho:μ1=μ2Ha:μ1<μ2Ha:μ1<μ2…arrow_forwardA scientist is studying the effect of a new type of exercise program on cardiovascular health. The scientist randomly assigns individuals to either the exercise program or a control group. The scientist wants to determine if the exercise program has a statistically significant effect on cardiovascular health. The scientist monitors cardiovascular health by measuring the blood pressure of each individual.arrow_forwardA study was undertaken to investigate the effectiveness of an aquarobic exercise program for patients with osteoarthritis. A convenience sample of 70 individuals with arthritis was selected, and each person was randomly assigned to one of two groups. The first group participated in a weekly aquarobic exercise program for 8 weeks; the second group served as a control. Several pieces of data were collected from the individuals, including their total cholesterol (mg). Determine if there is a significant difference in the mean cholesterol for the two groups (aquarobic & control) at the start of the study using a significance level of 0.10. Difference Sample Diff. Std. Error df Aquarobic - Control 2.698 7.3227 65.6844 • What hypotheses should be tested? Make sure to select the hypotheses which are written with notation consistent with the type of samples selected. H.: µd = l2 H.: µ1 = µ2 H.:µd H.: Hd > 0 Ha: H1 # H2 Ha:µ1 > µ2 Ha:Hd < 0 Ha:H1 < µs Ha: Hd # 0 = 0 H,:µ1 0 H.: µ1 = µ2 H.: µd •…arrow_forward
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