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Genetic Analysis: An Integrated Approach (3rd Edition)
- A population sample of 300 individuals is studied for the electrophoretic mobility of an enzyme that varies according to the genotype determined by 2 alleles, E and T of a single gene. The results are 7 individuals with genotype EE, 106 with genotype ET, and 187 with genotype TT. What are the allele frequencies of E and T, and what are the expected numbers of the 3 genotypes if random mating is assumed?arrow_forwardYou have collected and determined genotypes of 200 individuals from a population of thr fruit fly, Drosophila pseudoobscura. Your sequencing study revealed 20 individuals with genotype AA, 70 individuals with genotype Aa and 110 individuals with genotype aa. i) what are your theoretical expectations for the number of individuals with each genotype if the population is in Hardy-Weinberg equilibrium. ii) Based on the genotype counts observed, is there evidence that this population of fruit flies deviates from your theoretical expectations under Hardy-Weinberg equilibrium?arrow_forwardRefer to the figure above. In their investigation of natural selection on Mc1r alleles (the gene that determines coat color) in Arizona pocket mice, Hoekstra et al. determined the frequency of the D and d alleles in each population. They also determined the frequency of alleles for two neutral mitochondrial DNA genes (genes that do not affect and are not linked to coat color). Why did the researchers include the mitochondrial DNA genes as part of their experimental design? Allele change for the neutral mitochondrial genes serves as an experimental group and gives information on any general background genetic difference among these populations. Allele change for the neutral mitochondrial genes serves as a control and determines coat-color differences among these populations. Allele change for the neutral mitochondrial genes serves as an experimental group and gives information on coat-color differences among these populations. Allele…arrow_forward
- in a randomly mating laboratory population of Drosophila, 4% of the flies have black bodies, and 96% have brown bodies. Flies with brown bodies always have at least one parent with a brown body. What is the frequency of heterozygotes in this population? 0.04 0.16 0.08 0.32 The period gene of Drosophila melanogaster encodes for a stretch of Thr-Gly repeated in tandem. In natural populations, the three most common alleles encode for 17, 20 and 23 Thr-Gly repeats. The amplification by PCR of the allele encoding for 20 Thr-Gly repeats produces a fragment of 320 bp. Using the same set of primers, what is the size expected when amplifying the 17 Thr-Gly allele? 317 303 314 302 in a certain species of plant loci A, B and C have an additive effect on the colour of the flower. Alleles A, B, and C are dominant and alleles a, b and c are recessive. Knowing that a plant with genotype AAbbCc has a…arrow_forwardA researcher sequences the Pitx1 gene in a population of 100 stickleback fish that is known to affect dorsal spine length. He finds that the gene is NOT in Hardy-Weinberg equilibrium. There is an excess of homozygotes compared to expected. He then sequences 5 more loci scattered across the genome (on different chromosomes) but finds that these other loci are all in HW equilibrium. (That is, there was no difference between observed and expected frequencies). What is the most reasonable conclusion concerning the Pitx1 gene?arrow_forwardIn the fly speciation experiment described in class, Drosophila from a single culture was split into four isolated cultures, 2 raised on maltose food and two on starch food. After forty generations all possible crosses were done between maltose and starch flies and between the two starch populations. Flies from different food types had very low mating frequencies compared to flies from the same food type but flies from different starch populations only mated at a very slightly lower rate than flies from the same starch population. How would you interpret this finding? Group of answer choices A. allopatric speciation is more powerful than sympatric speciation B. flies are incapable of evolution C. drift causes divergence more rapidly than selection D. sympatric speciation is more powerful than allopatric speciation E. selection causes divergence more rapidly than driftarrow_forward
- A researcher is studying two fly populations. Population A have stubbly bristles that are shorter and blunter than population B and are ebony coloured with black bodies. This is because they are homozygous for a certain allele for the stubble gene which affects bristle length and homozygous for the ebony gene which affects body colour. Population B have longer tapered bristles than population A and are not stubbly in appearance. They are not ebony and have brown bodies. This is because they are homozygous for a different gene that affects bristle length to population A and are homozygous for the gene that affects body colour. Table 1: F1 ebony flies - 0 F1 non-ebony flies - 560 F1 stubble flies - 560 F1 non-stubble flies - 0 Draw two separate Punnett Squares to illustrate the P1 cross - one for the stubbly alleles and one for the ebony alleles showing the individual gametes of each parent and the combination in the resulting F1 offspring.arrow_forwardYou set up two populations of fruit flies (Drosophila) in the lab in large enclosures. One population is maintained in a high food condition in which food is constantly abundant and uniformly distributed, whereas the second population is maintained in a low food condition is which food is scarce and randomly distributed. You allow the populations to live and breed in the enclosures for 500 generations. Which of the following can you correctly predict to occur? a. the “sitter” allele (forS) will increase in the high food population. b. the “rover” allele (forR) will increase in the high food population. c. flies in the low food population will have higher levels of PKG compared to flies in the high food population. d. flies in the high food population will have higher levels of PKG compared to flies in the low food population. e. a and c f. b and d g. none of thesearrow_forwardThere are two incomplete-dominant alleles for petal color in a population of flowers. 36% of the flowers have red petals, 16% of the organisms have white petals, and 48% of the flowers have pink petals. What percentage of alleles in this population code for red petals (R)? how can i calculate it?arrow_forward
- Two SNPs are located in the short arm of chromosome 12. SNP1 has allele frequencies of 60% T and 40% C, and SNP2 has allele frequencies of 40% A and 60% G. What is the frequency of the haplotype T-G in a population if the two SNPs are in absolute linkage disequilibrium and if they are in linkage equilibrium?arrow_forwardThe ability to taste the compound PTC is controlled by a dominant allele T, while individuals homozygous for the recessive allele (t) cannot taste PTC. In a population consisting of 500 individuals, 347 are tasters and 153 are non-PTC tasters. Calculate the frequency of the T and t alleles in this population, and frequency of the genotypes. (Please train yourself to use the Hardy-Weinberg equation.) To present your answers, follow the format in the picture below.arrow_forwardThe ability to taste the compound PTC is controlled by a dominant allele T, while individuals homozygous for the recessive allele (t) cannot taste PTC. In a population consisting of 500 individuals, 347 are tasters and 153 are non-PTC tasters. Calculate the frequency of the T and t alleles in this population, and frequency of the genotypes. (Please train yourself to use the Hardy-Weinberg equation.)arrow_forward
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