Concept explainers
(a)
Interpretation:
Synthesis of the given
Concept introduction:
The Gabriel synthesis is an effective way to synthesize a primary amine (
(b)
Interpretation:
Synthesis of the given amine from an alkyl halide via a Gabriel synthesis is to be shown.
Concept introduction:
The Gabriel synthesis is an effective way to synthesize a primary amine (
(c)
Interpretation:
Synthesis of the given amine from an alkyl halide via Gabriel synthesis is to be shown.
Concept introduction:
Gabriel synthesis is an effective way to synthesize a primary amine (
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Check out a sample textbook solutionChapter 20 Solutions
Organic Chemistry: Principles and Mechanisms (Second Edition)
- The Gabriel–malonic ester synthesis, shown here, is used to make α-amino acids. Draw complete, detailed mechanisms for this set of reactions and draw the structure of the intermediate A.arrow_forwardAn imino chloride can be prepared from an amide according to the reaction shown here. Propose a mechanism for this reaction.arrow_forwardThe Gabriel synthesis of primary amines discussed in Chapter 20 involves hydrolysis under basic conditions to release the amine. As shown in the reactions below, the amine can also be released by (a) hydrolysis under acidic conditions and (b) treatment with hydrazine. Draw the complete, detailed mechanisms for these reactions.arrow_forward
- SYN) Suggest how you would carry out the synthesisshown here using any reagents necessary. Hint: Thesynthesis may require more than one synthetic step.arrow_forward(SYN) Show how to carry out the following conversion.Hint: Consider using a protecting group.arrow_forward(SYN) Show how to synthesize each of the following compounds beginning with malonic ester.arrow_forward
- (SYN) Show how to synthesize each of the following trisubstituted benzenes from a disubstituted benzenearrow_forward(SYN) Show how each of the following compounds can be synthesized from an acid chloride and either water, an alcohol, or an amine. For each reaction, provide the complete, detailed mechanism.arrow_forwardPlease predict the product of the following reaction, and draw the complete, detailed mechanism.arrow_forward
- Organic Chemistry: A Guided InquiryChemistryISBN:9780618974122Author:Andrei StraumanisPublisher:Cengage Learning