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The base sequences in mRNA that code for certain amino acids are Glu: GAA, GAG Val: GUU, GUC, GUA, GUG Met: AUG Trp: UGG Phe: UUU, UUC Asp: GAU, GAC These sequences are complementary to the sequences in DNA. a. Give the corresponding sequences in DNA for the amino acids listed above. b. Give a DNA sequence that would code for the peptide trp-glu-phe-met. c. How many different DNA sequences can code for the tetrapeptide in part b? d. What is the peptide that is produced from the DNA sequence T–A–C–C–T–G–A–A–G? e. What other DNA sequences would yield the same tripeptide as in part d?

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Chemistry: An Atoms First Approach

2nd Edition
Steven S. Zumdahl + 1 other
Publisher: Cengage Learning
ISBN: 9781305079243

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BuyFindarrow_forward

Chemistry: An Atoms First Approach

2nd Edition
Steven S. Zumdahl + 1 other
Publisher: Cengage Learning
ISBN: 9781305079243
Chapter 21, Problem 109E
Textbook Problem
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The base sequences in mRNA that code for certain amino acids are

Glu: GAA, GAG
Val: GUU, GUC, GUA, GUG
Met: AUG
Trp: UGG
Phe: UUU, UUC
Asp: GAU, GAC

These sequences are complementary to the sequences in DNA.

a. Give the corresponding sequences in DNA for the amino acids listed above.

b. Give a DNA sequence that would code for the peptide trp-glu-phe-met.

c. How many different DNA sequences can code for the tetrapeptide in part b?

d. What is the peptide that is produced from the DNA sequence T–A–C–C–T–G–A–A–G?

e. What other DNA sequences would yield the same tripeptide as in part d?

(a)

Interpretation Introduction

Interpretation:  The corresponding sequence in DNA for the given amino acid and the DNA sequences that code for the peptide, trp-glu-phe-met are to be stated. A different DNA sequence that can code for the tetrepeptide and tripeptide with the peptide that is produced is to be explained.

Concept introduction: A codon is defined as a sequence of three adjacent nucleotides which constitutes the genetic code that specifies the insertion of amino acid in a polypeptide. Tripeptide and tetrepeptide are composed of three or four peptides joined by peptide linkage. The given m-RNA base sequences are,

Glu: GAA, GAG

Val: GUU, GUC, GUA, GUG

Met: AUG

Trp: UGG

Phe: UUU, UUC

Asp: GAU, GAC

To determine: The corresponding sequence in DNA for the given amino acid.

Explanation of Solution

Explanation

The corresponding sequence in DNA for the given amino acid is shown below.

The four nucleotide bases of a DNA strand. These are guanine, thymine, cytosine and adenine. The nucleic acids base sequence can form a double stranded structure by matching base pairs with their complementary base sequence. Both the sequences are aligned antiparallel to each other. In DNA molecule, adenine (A) always pairs with thymine (T) and cytosine (C) always pairs with guanine (G) but in m-RNA adenine (A) always pairs with uracil (U) and cytosine (C) always pairs with guanine (G)...

(b)

Interpretation Introduction

Interpretation:  The corresponding sequence in DNA for the given amino acid and the DNA sequences that code for the peptide, trp-glu-phe-met are to be stated. A different DNA sequence that can code for the tetrepeptide and tripeptide with the peptide that is produced is to be explained.

Concept introduction: A codon is defined as a sequence of three adjacent nucleotides which constitutes the genetic code that specifies the insertion of amino acid in a polypeptide. Tripeptide and tetrepeptide are composed of three or four peptides joined by peptide linkage. The given m-RNA base sequences are,

Glu: GAA, GAG

Val: GUU, GUC, GUA, GUG

Met: AUG

Trp: UGG

Phe: UUU, UUC

Asp: GAU, GAC

To determine: The DNA sequences that code for the peptide, trp-glu-phe-met.

(c)

Interpretation Introduction

Interpretation:  The corresponding sequence in DNA for the given amino acid and the DNA sequences that code for the peptide, trp-glu-phe-met are to be stated. A different DNA sequence that can code for the tetrepeptide and tripeptide with the peptide that is produced is to be explained.

Concept introduction: A codon is defined as a sequence of three adjacent nucleotides which constitutes the genetic code that specifies the insertion of amino acid in a polypeptide. Tripeptide and tetrepeptide are composed of three or four peptides joined by peptide linkage. The given m-RNA base sequences are,

Glu: GAA, GAG

Val: GUU, GUC, GUA, GUG

Met: AUG

Trp: UGG

Phe: UUU, UUC

Asp: GAU, GAC

To determine: A different DNA sequences that can code for the tetrepeptide.

(d)

Interpretation Introduction

Interpretation:  The corresponding sequence in DNA for the given amino acid and the DNA sequences that code for the peptide, trp-glu-phe-met are to be stated. A different DNA sequence that can code for the tetrepeptide and tripeptide with the peptide that is produced is to be explained.

Concept introduction: A codon is defined as a sequence of three adjacent nucleotides which constitutes the genetic code that specifies the insertion of amino acid in a polypeptide. Tripeptide and tetrepeptide are composed of three or four peptides joined by peptide linkage. The given m-RNA base sequences are,

Glu: GAA, GAG

Val: GUU, GUC, GUA, GUG

Met: AUG

Trp: UGG

Phe: UUU, UUC

Asp: GAU, GAC

To determine: The peptide that is produced from the DNA sequences T-A-C-C-T-G-A-A-G.

(e)

Interpretation Introduction

Interpretation:  The corresponding sequence in DNA for the given amino acid and the DNA sequences that code for the peptide, trp-glu-phe-met are to be stated. A different DNA sequence that can code for the tetrepeptide and tripeptide with the peptide that is produced is to be explained.

Concept introduction: A codon is defined as a sequence of three adjacent nucleotides which constitutes the genetic code that specifies the insertion of amino acid in a polypeptide. Tripeptide and tetrepeptide are composed of three or four peptides joined by peptide linkage. The given m-RNA base sequences are,

Glu: GAA, GAG

Val: GUU, GUC, GUA, GUG

Met: AUG

Trp: UGG

Phe: UUU, UUC

Asp: GAU, GAC

To determine: The other DNA sequences to yield the same tripeptide as in part (d).

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Chapter 21 Solutions

Chemistry: An Atoms First Approach
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Ch. 21 - What are carbohydrates, and what are the monomers...Ch. 21 - Describe the structural differences between DNA...Ch. 21 - A confused student was doing an isomer problem and...Ch. 21 - For the following formulas, what types of...Ch. 21 - What is wrong with the following names? Give the...Ch. 21 - The following organic compounds cannot exist. Why?...Ch. 21 - If you had a group of hydrocarbons, what...Ch. 21 - Which of the functional groups in Table 21-4 can...Ch. 21 - A polypeptide is also called a polyamide. Nylon is...Ch. 21 - Give an example reaction that would yield the...Ch. 21 - Give an example reaction that would yield the...Ch. 21 - What is polystyrene? 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CH2 = CH ...Ch. 21 - Name each of the following alkenes or alkynes. a....Ch. 21 - Give the structure for each of the following. a....Ch. 21 - Give the structure for each of the following. a....Ch. 21 - Give the structure of each of the following...Ch. 21 - Cumene is the starting material for the industrial...Ch. 21 - Name each of the following. a. b. CH3CH2CH2CCl3 c....Ch. 21 - Name each of the following compounds. a. b. c. d....Ch. 21 - There is only one compound that is named...Ch. 21 - Consider the following four structures. a. Which...Ch. 21 - Which of the compounds in Exercises 25 and 27...Ch. 21 - Which of the compounds in Exercises 26 and 28...Ch. 21 - Draw all the structural isomers of C5H10. 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HCOOHCh. 21 - Draw a structural formula for each of the...Ch. 21 - Which of the following statements is(are) false?...Ch. 21 - Draw the isomer(s) specified. There may be more...Ch. 21 - Complete the following reactions. a. b. c. d.Ch. 21 - Reagents such as HCl, HBr, and HOH (H2O) can add...Ch. 21 - When toluene (C6H5CH3) reacts with chlorine gas in...Ch. 21 - Why is it preferable to produce chloroethane by...Ch. 21 - Using appropriate reactants, alcohols can be...Ch. 21 - Oxidation of an aldehyde yields a carboxylic acid:...Ch. 21 - How would you synthesize each of the following? a....Ch. 21 - What tests could you perform to distinguish...Ch. 21 - How would you synthesize the following esters? a....Ch. 21 - Complete the following reactions. a. 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