Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Question
Chapter 21, Problem 34P
Interpretation Introduction
Interpretation:
The way insulin stimulates glycogen synthesis should be explained.
Concept introduction:
When blood-glucose levels are high insulin stimulates glycogen synthesis by inactivating glycogen synthase kinase.
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Ingesting large amounts of glucose before a marathon might seem to be a good way of increasing the fuel stores. However, experienced runners do not ingest glucose before a race. What is the biochemical reason for their avoidance of this potential fuel? (Hint: Consider the effect of glucose ingestion on the level of insulin.)
Explain what biochemical pathway/metabolic processes are affected in insulin resistance?
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29. Synthesis signal. How does insulin stimulate glycogen synthesis?
Chapter 21 Solutions
Biochemistry
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- Correlate the importance of Citric Acid Cycle in maintaining the glucose hemeostasis.arrow_forwardFatty acids appear to stimulate insulin secretion to a much greater extent when glucose is also present. Why is this significant?arrow_forwardDiscuss the glycogen degradation. Give the three enzymes required for this process and their functions.arrow_forward
- Explain why insulin is required for adipocytes to synthesize triacylglycerols from fatty acids.arrow_forwardCompare and contrast glycogen synthesis/degradation in muscles as compared with the liver.arrow_forwardDiabetes Type 1 and Type 2 Applying signal transduction mechanisms in the context of Type I and Type II Diabetes. Describe the mechanisms by which a cell receives a message and translates it into short-term or long-term effects. Including the role of phosphorylation and feedback inhibition.arrow_forward
- Describe the role of insulin in lipid metabolism.arrow_forwardc) Cooperation between glycolysis and gluconeogenesis is important to ensure the glucose-subjected energy demands of specific cells are met. Explain this statement.arrow_forwardUnder FASTING state, how do the hormonal changes bring about the effect to maintain glucose homeostasis in the body through the pathways of GLYCOLYSIS and GLUCONEOGENESIS; GLYCOGENOLYSIS and GLYCOGENESIS? (Please describe the signaling pathways in detail. )arrow_forward
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