Concept explainers
(a) Interpretation:
The enzyme deoxyribonucleic acid (DNA) ligase has the ability to relax supercoiled circular deoxyribonucleic acid (DNA) in the presence of AMP, but not in the absence of AMP. The mechanism of this reaction and reason for its dependence on AMP should be explained.
Concept introduction:
The enzyme DNA ligase is accountable for joining the nick in two deoxyribonucleic acid (DNA) strands. This is done through the process nick translation.
The supercoiling of deoxyribonucleic acid (DNA) is the demonstration of a structural strain in deoxyribonucleic acid (DNA). This is done by twisting of the axis upon itself and helps in compacting the DNA tightly in an organized manner.
(b) Interpretation:
The reason behind relaxation of the supercoiled deoxyribonucleic acid (DNA) should be explained.
Concept introduction:
The enzyme DNA ligase is accountable for joining the nick in two deoxyribonucleic acid (DNA) strands. This is done through the process nick translation.
The supercoiling of deoxyribonucleic acid (DNA) is the demonstration of a structural strain in deoxyribonucleic acid (DNA). This is done by twisting of the axis upon itself and helps in compacting the DNA tightly in an organized manner.
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