Mechanism for the given transformation need to be drawn and the reagents used for the given transformation has to be identified. Concept introduction: When compound containing active methylene group is treated with LDA , it undergoes deprotonation at the α carbon to form carbanion. The carbanion can undergo alkylation with any alkyl halide to give the product where the alkyl group is substituted in the α carbon. Deprotonation of α carbon to form carbanion Alkylation of the carbanion

Question

Want to see the full answer?

Answer 1

Question

Chapter 22, Problem 93PP

(a)

Interpretation Introduction

Interpretation:

Mechanism for the given transformation need to be drawn and the reagents used for the given transformation has to be identified.

Concept introduction:

When compound containing active methylene group is treated with LDA , it undergoes deprotonation at the α carbon to form carbanion. The carbanion can undergo alkylation with any alkyl halide to give the product where the alkyl group is substituted in the α carbon.

Deprotonation of α carbon to form carbanion

Alkylation of the carbanion

(b)

Interpretation Introduction

Interpretation:

Mechanism for the given transformation need to be drawn and the reagents used for the given transformation has to be identified.

Concept introduction:

Cyanation is a process in which cyanide is substituted via SN2 reaction. When a compound containing active methylene group is treated with LDA , a carbanion is formed. The carbanion can undergo alkylation when treated with alkyl halide. The nitrile group can be hydrolyzed to give carboxylic acid.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 2

Question

Chapter 22, Problem 93PP

(a)

Interpretation Introduction

Interpretation:

Mechanism for the given transformation need to be drawn and the reagents used for the given transformation has to be identified.

Concept introduction:

When compound containing active methylene group is treated with LDA , it undergoes deprotonation at the α carbon to form carbanion. The carbanion can undergo alkylation with any alkyl halide to give the product where the alkyl group is substituted in the α carbon.

Deprotonation of α carbon to form carbanion

Alkylation of the carbanion

(b)

Interpretation Introduction

Interpretation:

Mechanism for the given transformation need to be drawn and the reagents used for the given transformation has to be identified.

Concept introduction:

Cyanation is a process in which cyanide is substituted via SN2 reaction. When a compound containing active methylene group is treated with LDA , a carbanion is formed. The carbanion can undergo alkylation when treated with alkyl halide. The nitrile group can be hydrolyzed to give carboxylic acid.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 3

Question

Chapter 22, Problem 93PP

(a)

Interpretation Introduction

Interpretation:

Mechanism for the given transformation need to be drawn and the reagents used for the given transformation has to be identified.

Concept introduction:

When compound containing active methylene group is treated with LDA , it undergoes deprotonation at the α carbon to form carbanion. The carbanion can undergo alkylation with any alkyl halide to give the product where the alkyl group is substituted in the α carbon.

Deprotonation of α carbon to form carbanion

Alkylation of the carbanion

(b)

Interpretation Introduction

Interpretation:

Mechanism for the given transformation need to be drawn and the reagents used for the given transformation has to be identified.

Concept introduction:

Cyanation is a process in which cyanide is substituted via SN2 reaction. When a compound containing active methylene group is treated with LDA , a carbanion is formed. The carbanion can undergo alkylation when treated with alkyl halide. The nitrile group can be hydrolyzed to give carboxylic acid.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Chapter 22, Problem 93PP

(a)

Interpretation Introduction

Interpretation:

Mechanism for the given transformation need to be drawn and the reagents used for the given transformation has to be identified.

Concept introduction:

When compound containing active methylene group is treated with LDA , it undergoes deprotonation at the α carbon to form carbanion. The carbanion can undergo alkylation with any alkyl halide to give the product where the alkyl group is substituted in the α carbon.

Deprotonation of α carbon to form carbanion

Alkylation of the carbanion

(b)

Interpretation Introduction

Interpretation:

Mechanism for the given transformation need to be drawn and the reagents used for the given transformation has to be identified.

Concept introduction:

Cyanation is a process in which cyanide is substituted via SN2 reaction. When a compound containing active methylene group is treated with LDA , a carbanion is formed. The carbanion can undergo alkylation when treated with alkyl halide. The nitrile group can be hydrolyzed to give carboxylic acid.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 5

Chapter 22, Problem 93PP

(a)

Interpretation Introduction

Interpretation:

Mechanism for the given transformation need to be drawn and the reagents used for the given transformation has to be identified.

Concept introduction:

When compound containing active methylene group is treated with LDA , it undergoes deprotonation at the α carbon to form carbanion. The carbanion can undergo alkylation with any alkyl halide to give the product where the alkyl group is substituted in the α carbon.

Deprotonation of α carbon to form carbanion

Alkylation of the carbanion

(b)

Interpretation Introduction

Interpretation:

Mechanism for the given transformation need to be drawn and the reagents used for the given transformation has to be identified.

Concept introduction:

Cyanation is a process in which cyanide is substituted via SN2 reaction. When a compound containing active methylene group is treated with LDA , a carbanion is formed. The carbanion can undergo alkylation when treated with alkyl halide. The nitrile group can be hydrolyzed to give carboxylic acid.

Answer 6

Chapter 22, Problem 93PP

(a)

Interpretation Introduction

Interpretation:

Mechanism for the given transformation need to be drawn and the reagents used for the given transformation has to be identified.

Concept introduction:

When compound containing active methylene group is treated with LDA , it undergoes deprotonation at the α carbon to form carbanion. The carbanion can undergo alkylation with any alkyl halide to give the product where the alkyl group is substituted in the α carbon.

Deprotonation of α carbon to form carbanion

Alkylation of the carbanion

Answer 7

Chapter 22, Problem 93PP

(a)

Interpretation Introduction

Interpretation:

Mechanism for the given transformation need to be drawn and the reagents used for the given transformation has to be identified.

Concept introduction:

When compound containing active methylene group is treated with LDA , it undergoes deprotonation at the α carbon to form carbanion. The carbanion can undergo alkylation with any alkyl halide to give the product where the alkyl group is substituted in the α carbon.

Deprotonation of α carbon to form carbanion

Alkylation of the carbanion

Answer 8

(b)

Interpretation Introduction

Interpretation:

Mechanism for the given transformation need to be drawn and the reagents used for the given transformation has to be identified.

Concept introduction:

Cyanation is a process in which cyanide is substituted via SN2 reaction. When a compound containing active methylene group is treated with LDA , a carbanion is formed. The carbanion can undergo alkylation when treated with alkyl halide. The nitrile group can be hydrolyzed to give carboxylic acid.

Answer 9

(b)

Interpretation Introduction

Interpretation:

Mechanism for the given transformation need to be drawn and the reagents used for the given transformation has to be identified.

Concept introduction:

Cyanation is a process in which cyanide is substituted via SN2 reaction. When a compound containing active methylene group is treated with LDA , a carbanion is formed. The carbanion can undergo alkylation when treated with alkyl halide. The nitrile group can be hydrolyzed to give carboxylic acid.

Answer 10

Expert Solution & Answer

Answer 11

Expert Solution & Answer

Answer 12

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 13

Ch. 22.1 - Prob. 1CC Ch. 22.1 - Prob. 2CC Ch. 22.1 - Prob. 3CC Ch. 22.1 - Prob. 1LTS Ch. 22.1 - Prob. 4PTS Ch. 22.1 - Prob. 5ATS Ch. 22.1 - Prob. 6CC Ch. 22.1 - Prob. 7CC Ch. 22.1 - Prob. 8CC Ch. 22.2 - Prob. 9CC

Want to see the full answer?

Chapter 22 Solutions