Concept explainers
(a)
Interpretation:
The role of acetyl-CoA in the reactions of Ketogenesis should be determined.
Concept introduction:
Ketogenesis is a process by which acetyl CoA is converted into
Ketone bodies are
Acetoacetate, acetone and
(b)
Interpretation:
The number of acetyl-CoA molecules which are used in the production of ketone bodies should be determined.
Concept introduction:
Ketogenesis is a process by which acetyl CoA is converted into ketone bodies.
Ketone bodies are metabolic products that are produced in excess during excessive breakdown of fatty acids. They are water soluble and energy yielding. In a normal man, concentration of ketone bodies in the blood is usually less than
Acetoacetate, acetone and
(c)
Interpretation:
The essential role of ketone bodies during prolonged starvation should be determined.
Concept introduction:
Ketogenesis is a process by which acetyl CoA is converted into ketone bodies.
Ketone bodies are metabolic products that are produced in excess during excessive breakdown of fatty acids. They are water soluble and energy yielding. In a normal man, concentration of ketone bodies in the blood is usually less than
Acetoacetate, acetone and
Gluconeogenesis is the process of formation of glucose from non-carbohydrate sources. The process occurs only in liver and kidney, partially occurs in cytoplasm and in mitochondria
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FUND.OF GEN CHEM CHAP 1-13 W/ACCESS
- Where does the carbon come from that is used to synthesize ketone bodies? a) Acetyl-CoA generated by decarboxylation of pyruvate b) Acetyl-CoA generated by deamination of amino acids c) Acetyl-CoA generated by beta-oxidation of fatty acids.arrow_forwardKetone bodies are exported from liver for use by other tissues. Because many tissues can synthesize ketone bodies, what enzymatic property of liver might contribute to its special ability to export these compounds?arrow_forwardWhy is oxaloacetate depletion from the TCA cycle important for the initiation of ketogenesis? What causes this oxaloacetate depletion? What tissue type in our body is this oxaloacetate depletion found and why is it not found in other tissues?arrow_forward
- How would the rapid accumulation of succinyl-CoA affect the rate of glucose oxidation?arrow_forwardDiscuss ketogenesis in details and also specify the ketone bodies.arrow_forwardThe body doesn’t have a reserve of proteins or amino acids for energy production. Which class of protein may be used initially during fasting to maintain glucose and energy levels? What is the difference between a glucogenic and ketogenic amino acid and why are both important during fasting?arrow_forward
- BiochemistryBiochemistryISBN:9781305577206Author:Reginald H. Garrett, Charles M. GrishamPublisher:Cengage Learning