Genetics: Analysis and Principles
5th Edition
ISBN: 9780073525341
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 25, Problem 15CONQ
What would you predict to be the
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A maternal effect gene in Drosophila, called torso, is found as a recessive allele that prevents the correct development of anterior- and posterior-most structures. A wild-type (homozygous) male is crossed to a female of unknown genotype. This mating produces 100% larva that are missing their anterior- and posterior-most structures and therefore die during early development. What is the genotype and phenotype of the female fly in this cross? What are the genotypes and phenotypes of the female fly’s parents? Show COMPLETE cross.
A maternal effect gene in Drosophila, called torso, is found as a recessive allele that prevents the correct development of anterior- and posterior-most structures. A wild-type (homozygous) male iscrossed to a female of unknown genotype. This mating produces 100% larva that are missing theiranterior- and posterior-most structures and therefore die during early development.
What is the genotype and phenotype of the female fly in this cross? What are the genotypes andphenotypes of the female fly’s parents? Show COMPLETE cross.
Maternal genotype:Paternal genotype:F1 genotype:F1 phenotype:
In Drosophila subobscura, the presence of a recessive gene called grandchildless (gs) causes the offspring of homozygous females, but not those of homozygous males, to be sterile. Can you offer an explanation as to why females and not males are affected by the mutant gene?
Chapter 25 Solutions
Genetics: Analysis and Principles
Ch. 25.1 - Prob. 1COMQCh. 25.1 - Prob. 2COMQCh. 25.1 - Which of the following is the correct order for...Ch. 25.2 - Prob. 1COMQCh. 25.2 - Prob. 2COMQCh. 25.2 - Prob. 3COMQCh. 25.2 - Prob. 4COMQCh. 25.3 - Prob. 1COMQCh. 25.3 - Prob. 2COMQCh. 25.3 - 3. Myogenic bHLH proteins are ___________ that...
Ch. 25.4 - Prob. 1COMQCh. 25.4 - Prob. 2COMQCh. 25.5 - 1. A key event that initially determines female or...Ch. 25.5 - Prob. 2COMQCh. 25 - 1. What four types of cellular processes must...Ch. 25 - Prob. 2CONQCh. 25 - Prob. 3CONQCh. 25 - 4. Which of the following statement(s) is/are true...Ch. 25 - Discuss the morphological differences between the...Ch. 25 - Prob. 6CONQCh. 25 - Explain what a morphogen is, and describe how it...Ch. 25 - 8. What is positional information? Discuss three...Ch. 25 - Prob. 9CONQCh. 25 - Prob. 10CONQCh. 25 - 11. Describe the function of the Bicoid protein....Ch. 25 - With regard to development, what are the roles of...Ch. 25 - Discuss the role of homeotic genes in development....Ch. 25 - Describe the molecular features of the homeobox...Ch. 25 - What would you predict to be the phenotype of...Ch. 25 - Prob. 16CONQCh. 25 - If a mutation in a homeotic gene produced the...Ch. 25 - 18. Explain how loss-of-function mutations in the...Ch. 25 - What is the difference between a maternal-effect...Ch. 25 - Prob. 20CONQCh. 25 - Prob. 21CONQCh. 25 - Prob. 22CONQCh. 25 - 23. Discuss the similarities and differences...Ch. 25 - 24. What is cell differentiation? Discuss the role...Ch. 25 - Prob. 25CONQCh. 25 - What is a totipotent cell? In each of the...Ch. 25 - 27. What is a meristem? Explain the role of...Ch. 25 - Prob. 28CONQCh. 25 - Predict the phenotypic consequences of each of the...Ch. 25 - 30. Explain how alternative splicing affects sex...Ch. 25 - Prob. 1EQCh. 25 - Compare and contrast the experimental advantages...Ch. 25 - 3. What is meant by the term cell fate? What is a...Ch. 25 - 4. Explain why a cell lineage diagram is necessary...Ch. 25 - Explain the rationale behind the use of the bag of...Ch. 25 - Prob. 6EQCh. 25 - Take a look at question 2 in More Genetic TIPS...Ch. 25 - All of the homeotic genes inDrosophilahave been...Ch. 25 - Prob. 9EQCh. 25 - wo techniques commonly used to study the...Ch. 25 - Prob. 11EQCh. 25 - Prob. 12EQCh. 25 - 13. Another way to study the role of proteins...Ch. 25 - 14. Why have geneticists used reverse genetics to...Ch. 25 - Prob. 1QSDCCh. 25 - Prob. 2QSDCCh. 25 - Prob. 3QSDC
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- Suppose a researcher has three different Drosophila strains that have mutations in the bicoid gene called bicoid-A, bicoid-B, and bicoid-C; the wild type is designated bicoid +. To study these mutations, phenotypically normal female flies that are homozygous for the given bicoid mutation were obtained, and their oocytes were analyzed using a Northern blot to determine the size and/or amount of the bicoid mRNA and in situ hybridization to determine the bicoid mRNA location within the oocyte. A wild-type strain was also analyzed as a control. In both cases, the probe was complementary to the bicoid mRNA and the results are shown below. (Anterior is on the left; posterior is on the right.) Northern blot 1 2 - 3 4 In situ hybridization Wild type Lane 1. Wild type (bicoid*) Lane 2. bicoid-A Lane 3. bicoid-B Lane 4. bicoid-C bicoid-B bicoid-A bicoid-C Which mutation is likely to cause the embryo to develop two "anterior" ends? bicoid-B Obicoid-A bicoid-Carrow_forwardIn drosophila, a recessive mutation (m-) of a maternal effect gene results in an abnormal phenotype wherein homozygous (m-m-) females produce eggs that cannot support embryonic development. Homozygous (m-m-) males, however, can still produce viable sperm. Using m+ to denote a normal gene, determine the genotypes and phenotypes of the F1s produce by a cross between a heterozygous female and a recessive male. From the offspring, backcross the recessive female with the paternal strain. 1. What are the genotypes and phenotypes of the F2s? 2. If m-m- females produce useless eggs, then how are m-m- produced?arrow_forwardIn drosophila, a recessive mutation (m-) of a maternal effect gene results in an abnormal phenotype wherein homozygous (m-m-) females produce eggs that cannot support embryonic development. Homozygous (m-m-) males, however, can still produce viable sperm. Using m+ to denote a normal gene, determine the genotypes and phenotypes of the F1s produce by a cross between a heterozygous female and a recessive male. From the offspring, backcross the recessive female with the paternal strain. What are the genotypes and phenotypes of the F2s? Show COMPLETE cross for both cases. If m-m- females produce useless eggs, then how are m-m- produced?arrow_forward
- In drosophila, a recessive mutation (m-) of a maternal effect gene results in an abnormalphenotype wherein homozygous (m-m-) females produce eggs that cannot support embryonicdevelopment. Homozygous (m-m-) males, however, can still produce viable sperm. Using m+ todenote a normal gene, determine the genotypes and phenotypes of the F1s produce by a crossbetween a heterozygous female and a recessive male. From the offspring, backcross the recessivefemale with the paternal strain. What are the genotypes and phenotypes of the F2s?arrow_forwardIn drosophila, a recessive mutation (m-) of a maternal effect gene results in an abnormal phenotype wherein homozygous (m-m-) females produce eggs that cannot support embryonic development. Homozygous (m-m-) males, however, can still produce viable sperm. (A) Using m+ to denote a normal gene, determine the genotypes and phenotypes of the F1s produce by a cross between a heterozygous female and a recessive male. (B) From the offspring, backcross the recessive female with the paternal strain. What are the genotypes and phenotypes of the F2s? (C) If m-m- females produce useless eggs, then how are m-m- produced?arrow_forwardA Drosophila embryo dies during early embryogenesis due to arecessive allele of a maternal effect gene called bicoid. The wildtypeallele is designated bicoid +. What are the genotypes and phenotypesof the embryo’s mother and maternal grandparents?arrow_forward
- The normal sequence of markers on a certain Drosophila chromosome is ABCDE*FGHIJK, where the asterisk represents the centromere. Some flies were isolated with a chromosome aberration that has the following structure: ABCDE*FIJK . This represents a O a) deletion of GH segment O b) inversion of GH segment O c) deletion O d) deletion of centromerearrow_forwardOur understanding of maternal effect genes has been greatly aided by their identification in experimental organisms such as Drosophila melanogaster and Caenorhabditis elegans. In experimental organisms with a short generation time, geneticists have successfully searched for mutant alleles that prevent the normal process of embryonic development. In many cases, the offspring die at early embryonic or larval stages. These are called maternal effect lethal alleles. How would a researcher identify a mutation that produced a recessive maternal effect lethal allele?arrow_forwardThe Drosophila gene Sex lethal (Sxl) is deserving of itsname. Certain alleles have no effect on XY animals butcause XX animals to die early in development. Other alleles have no effect on XX animals but cause XY animals to die early in development. Thus, some Sxl allelesare lethal to females, while others are lethal to males.a. Would you expect a null mutation in Sxl to causelethality in males or in females? b. Why do Sxl alleles of either type cause lethality ina specific sex?The gene transformer (tra) gets its name from sexualtransformation, as some tra alleles can change XXanimals into morphological males, while other traalleles can change XY animals into morphologicalfemales.c. Which of these sex transformations would becaused by null alleles of tra and which would becaused by constitutively active alleles of tra?d. In contrast with Sxl, null tra mutations do notcause lethality either in XX or in XY animals.However, the Sxl protein regulates the productionof the Tra protein. Why…arrow_forward
- Why is it that mutations in bicoid and nanos exhibit genetic maternal effect in Drosophila (a mutation in the maternal parent produces a phenotype that shows up in the offspring), but mutations in runt and gooseberry do not?arrow_forwardHow do we know that the mutant Bar-eye phenotype in Drosophila is due to a duplicated gene region rather than to a change in the nucleotide sequence of a gene?arrow_forwardIt is assumed that in Drosophila the following genotypes produce phenotypes. َA- B- = Red color A- bb = Plum color aa B- = Magenta color aa bb = White color The third latent genotype, cc, kills homozygous Plums, but has no effect on other genotypes. Also, genotype C- does not produce a large phenotype. If first-generation Drosophilas are heterozygous for all of these genes and interbreed, what phenotypic ratios are expected in society?arrow_forward
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