(a) Interpretation: The structure of UDP-glucose is to be determined. Concept introduction: The structure of UDP-glucose is similar to UDP-galactose only the galactose ring is replaced with glucose.

Question

Want to see the full answer?

Answer 1

Question

Chapter 25, Problem 25.16P

Interpretation Introduction

(a)

Interpretation:

The structure of UDP-glucose is to be determined.

Concept introduction:

The structure of UDP-glucose is similar to UDP-galactose only the galactose ring is replaced with glucose.

Interpretation Introduction

(b)

Interpretation:

The reaction for the sucrose biosynthesis is to be drawn and reaction occurs with inversion or retention of stereochemistry at anomeric carbon of UDP-glucose is to be determined.

Concept introduction:

The sucrose biosynthesis is occurred by nucleophilic attack of fructose to anomeric carbon of UDP-glucose and the reaction proceeds through SN1 reaction by formation of oxygen stabilized carbocation. The stereochemistry of at anomreic carbon can be determined by the approach of attacking fructose on anomeric carbon.

Interpretation Introduction

(c)

Interpretation:

The role of an arginine (Arg) residue and lysine (Lys) residue in the synthase mechanism is to be explained.

Concept introduction:

The negative charge on phosphate esters can be stabilized by metal ion or the positively charged groups on the active-site amino acids.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

Consider the tetrasaccharide stachyose drawn below. Stachyose is found in white jasmine,soybeans, and lentils. Because humans cannot digest it, its consumption causes flatulence. a. Is stachyose a reducing sugar?b. What product is formed when stachyose is treated with excess CH3I, Ag2O?c. What products are formed when the product in (e) is treated with H3O+?

C. Trehalose and maltose are both dimers of glucose. However, they have considereably different reactivities. Concisely explain why these differences are observed. HO НО НО HO Но HO OH Он HO OHOH Но trehalose maltose 1. Malthose is a reducing sugar while trehalose is not. 2. Trehalose is very resistant to acid hydrolysis while maltose can be acid-hydrolyzed with ease.

a. How many stereogenic centers are present in α-D-galactose? b. Label the hemiacetal carbon in α-D-galactose. c. Draw the structure of β-D-galactose. d. Draw the structure of the polyhydroxy aldehyde that cyclizes to α- and β-D-galactose.

Answer 2

Question

Chapter 25, Problem 25.16P

Interpretation Introduction

(a)

Interpretation:

The structure of UDP-glucose is to be determined.

Concept introduction:

The structure of UDP-glucose is similar to UDP-galactose only the galactose ring is replaced with glucose.

Interpretation Introduction

(b)

Interpretation:

The reaction for the sucrose biosynthesis is to be drawn and reaction occurs with inversion or retention of stereochemistry at anomeric carbon of UDP-glucose is to be determined.

Concept introduction:

The sucrose biosynthesis is occurred by nucleophilic attack of fructose to anomeric carbon of UDP-glucose and the reaction proceeds through SN1 reaction by formation of oxygen stabilized carbocation. The stereochemistry of at anomreic carbon can be determined by the approach of attacking fructose on anomeric carbon.

Interpretation Introduction

(c)

Interpretation:

The role of an arginine (Arg) residue and lysine (Lys) residue in the synthase mechanism is to be explained.

Concept introduction:

The negative charge on phosphate esters can be stabilized by metal ion or the positively charged groups on the active-site amino acids.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 3

Question

Chapter 25, Problem 25.16P

Interpretation Introduction

(a)

Interpretation:

The structure of UDP-glucose is to be determined.

Concept introduction:

The structure of UDP-glucose is similar to UDP-galactose only the galactose ring is replaced with glucose.

Interpretation Introduction

(b)

Interpretation:

The reaction for the sucrose biosynthesis is to be drawn and reaction occurs with inversion or retention of stereochemistry at anomeric carbon of UDP-glucose is to be determined.

Concept introduction:

The sucrose biosynthesis is occurred by nucleophilic attack of fructose to anomeric carbon of UDP-glucose and the reaction proceeds through SN1 reaction by formation of oxygen stabilized carbocation. The stereochemistry of at anomreic carbon can be determined by the approach of attacking fructose on anomeric carbon.

Interpretation Introduction

(c)

Interpretation:

The role of an arginine (Arg) residue and lysine (Lys) residue in the synthase mechanism is to be explained.

Concept introduction:

The negative charge on phosphate esters can be stabilized by metal ion or the positively charged groups on the active-site amino acids.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Chapter 25, Problem 25.16P

Interpretation Introduction

(a)

Interpretation:

The structure of UDP-glucose is to be determined.

Concept introduction:

The structure of UDP-glucose is similar to UDP-galactose only the galactose ring is replaced with glucose.

Interpretation Introduction

(b)

Interpretation:

The reaction for the sucrose biosynthesis is to be drawn and reaction occurs with inversion or retention of stereochemistry at anomeric carbon of UDP-glucose is to be determined.

Concept introduction:

The sucrose biosynthesis is occurred by nucleophilic attack of fructose to anomeric carbon of UDP-glucose and the reaction proceeds through SN1 reaction by formation of oxygen stabilized carbocation. The stereochemistry of at anomreic carbon can be determined by the approach of attacking fructose on anomeric carbon.

Interpretation Introduction

(c)

Interpretation:

The role of an arginine (Arg) residue and lysine (Lys) residue in the synthase mechanism is to be explained.

Concept introduction:

The negative charge on phosphate esters can be stabilized by metal ion or the positively charged groups on the active-site amino acids.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 5

Chapter 25, Problem 25.16P

Interpretation Introduction

(a)

Interpretation:

The structure of UDP-glucose is to be determined.

Concept introduction:

The structure of UDP-glucose is similar to UDP-galactose only the galactose ring is replaced with glucose.

Interpretation Introduction

(b)

Interpretation:

The reaction for the sucrose biosynthesis is to be drawn and reaction occurs with inversion or retention of stereochemistry at anomeric carbon of UDP-glucose is to be determined.

Concept introduction:

The sucrose biosynthesis is occurred by nucleophilic attack of fructose to anomeric carbon of UDP-glucose and the reaction proceeds through SN1 reaction by formation of oxygen stabilized carbocation. The stereochemistry of at anomreic carbon can be determined by the approach of attacking fructose on anomeric carbon.

Interpretation Introduction

(c)

Interpretation:

The role of an arginine (Arg) residue and lysine (Lys) residue in the synthase mechanism is to be explained.

Concept introduction:

The negative charge on phosphate esters can be stabilized by metal ion or the positively charged groups on the active-site amino acids.

Answer 6

Chapter 25, Problem 25.16P

Interpretation Introduction

(a)

Interpretation:

The structure of UDP-glucose is to be determined.

Concept introduction:

The structure of UDP-glucose is similar to UDP-galactose only the galactose ring is replaced with glucose.

Answer 7

Chapter 25, Problem 25.16P

Interpretation Introduction

(a)

Interpretation:

The structure of UDP-glucose is to be determined.

Concept introduction:

The structure of UDP-glucose is similar to UDP-galactose only the galactose ring is replaced with glucose.

Answer 8

Interpretation Introduction

(b)

Interpretation:

The reaction for the sucrose biosynthesis is to be drawn and reaction occurs with inversion or retention of stereochemistry at anomeric carbon of UDP-glucose is to be determined.

Concept introduction:

The sucrose biosynthesis is occurred by nucleophilic attack of fructose to anomeric carbon of UDP-glucose and the reaction proceeds through SN1 reaction by formation of oxygen stabilized carbocation. The stereochemistry of at anomreic carbon can be determined by the approach of attacking fructose on anomeric carbon.

Answer 9

Interpretation Introduction

(b)

Interpretation:

The reaction for the sucrose biosynthesis is to be drawn and reaction occurs with inversion or retention of stereochemistry at anomeric carbon of UDP-glucose is to be determined.

Concept introduction:

The sucrose biosynthesis is occurred by nucleophilic attack of fructose to anomeric carbon of UDP-glucose and the reaction proceeds through SN1 reaction by formation of oxygen stabilized carbocation. The stereochemistry of at anomreic carbon can be determined by the approach of attacking fructose on anomeric carbon.

Answer 10

Interpretation Introduction

(c)

Interpretation:

The role of an arginine (Arg) residue and lysine (Lys) residue in the synthase mechanism is to be explained.

Concept introduction:

The negative charge on phosphate esters can be stabilized by metal ion or the positively charged groups on the active-site amino acids.

Answer 11

Interpretation Introduction

(c)

Interpretation:

The role of an arginine (Arg) residue and lysine (Lys) residue in the synthase mechanism is to be explained.

Concept introduction:

The negative charge on phosphate esters can be stabilized by metal ion or the positively charged groups on the active-site amino acids.

Answer 12

Expert Solution & Answer

Answer 13

Expert Solution & Answer

Answer 14

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 15

Ch. 25 - Prob. 25.1P Ch. 25 - Prob. 25.2P Ch. 25 - Prob. 25.3P Ch. 25 - Prob. 25.4P Ch. 25 - Prob. 25.5P Ch. 25 - Prob. 25.6P Ch. 25 - Prob. 25.7P Ch. 25 - Prob. 25.8P Ch. 25 - Prob. 25.9P Ch. 25 - Prob. 25.10P

(a) Interpretation: The structure of UDP-glucose is to be determined. Concept introduction: The structure of UDP-glucose is similar to UDP-galactose only the galactose ring is replaced with glucose.

Solution Summary: The author explains that the structure of UDP-glucose is determined from the same stereochemistry at anomeric carbon.

Concept explainers

Videos

(a)

Interpretation:

The structure of UDP-glucose is to be determined.

Concept introduction:

The structure of UDP-glucose is similar to UDP-galactose only the galactose ring is replaced with glucose.

(c)

Interpretation:

The role of an arginine (Arg) residue and lysine (Lys) residue in the synthase mechanism is to be explained.

Concept introduction:

The negative charge on phosphate esters can be stabilized by metal ion or the positively charged groups on the active-site amino acids.

Want to see the full answer?

Chapter 25 Solutions

(a) Interpretation: The structure of UDP-glucose is to be determined. Concept introduction: The structure of UDP-glucose is similar to UDP-galactose only the galactose ring is replaced with glucose.

Solution Summary: The author explains that the structure of UDP-glucose is determined from the same stereochemistry at anomeric carbon.

Concept explainers

Videos

(a) Interpretation: The structure of UDP-glucose is to be determined. Concept introduction: The structure of UDP-glucose is similar to UDP-galactose only the galactose ring is replaced with glucose.

(c) Interpretation: The role of an arginine (Arg) residue and lysine (Lys) residue in the synthase mechanism is to be explained. Concept introduction: The negative charge on phosphate esters can be stabilized by metal ion or the positively charged groups on the active-site amino acids.

Want to see the full answer?

Chapter 25 Solutions

(a)

Interpretation:

The structure of UDP-glucose is to be determined.

Concept introduction:

The structure of UDP-glucose is similar to UDP-galactose only the galactose ring is replaced with glucose.

(c)

Interpretation:

The role of an arginine (Arg) residue and lysine (Lys) residue in the synthase mechanism is to be explained.

Concept introduction:

The negative charge on phosphate esters can be stabilized by metal ion or the positively charged groups on the active-site amino acids.