Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 25.1, Problem 3COMQ
Which of the following is not a common explanation for a dominant disorder?
a. Haploinsufficiency
b. A change in chromosome number
c. A gain-of-function mutation
d. A dominant-negative mutation
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Students have asked these similar questions
Locus heterogeneity refers to a genetic disorder thata. has a heterogeneous phenotype.b. is caused by mutations in two or more different genes.c. involves a structural change in multiple chromosomes.d. is inherited from both parents.
Polydactyly is a condition in which a person has extra fingersand/or toes. It is caused by a dominant allele. If a person carriesthis allele but does not have any extra fingers or toes, this is anexample ofa. haploinsufficiency.b. a dominant negative mutation.c. incomplete penetrance.d. a gain-of-function mutation.
The set of specific alleles on a single chromosome is known as what?
a.
A phenotype
b.
Diploidy
c.
A genetic locus
d.
A haplotype
Chapter 25 Solutions
Genetics: Analysis and Principles
Ch. 25.1 - Which of the following wouldnotbe consistent with...Ch. 25.1 - 2. Assuming complete penetrance, which type of...Ch. 25.1 - 3. Which of the following is not a common...Ch. 25.1 - Prob. 4COMQCh. 25.2 - Prob. 1COMQCh. 25.2 - Haplotype association studies are aimed at the...Ch. 25.3 - 1. Which of the following is not a method used in...Ch. 25.3 - 2. Which of the following prenatal genetic testing...Ch. 25.4 - Prob. 1COMQCh. 25.5 - 1. An oncogene is produced from a ________that has...
Ch. 25.5 - Which of the following is a type of genetic change...Ch. 25.5 - 3. Tumor-suppressor genes promote cancer...Ch. 25.5 - 4. Normal (nonmutant) tumor-suppressor genes often...Ch. 25.5 - Prob. 5COMQCh. 25.6 - Prob. 1COMQCh. 25 - 1. With regard to pedigree analysis, make a list...Ch. 25 - 2. Explain, at the molecular level, why human...Ch. 25 - 3. Many genetic disorders exhibit locus...Ch. 25 - Prob. 4CONQCh. 25 - Prob. 5CONQCh. 25 - Figure 25.1 illustrates albinism in two different...Ch. 25 - Prob. 7CONQCh. 25 - Prob. 8CONQCh. 25 - Ehler-Danlos syndrome is a rare disorder caused by...Ch. 25 - 10. Hurler syndrome is due to a mutation in a gene...Ch. 25 - Like Hurler syndrome, Fabry disease involves an...Ch. 25 - Achondroplasia is a rare form of dwarfism caused...Ch. 25 - Prob. 13CONQCh. 25 - 14. Marfan syndrome is due to a mutation in a...Ch. 25 - 15. Sandhoff disease is due to a mutation in a...Ch. 25 - Describe the two assumptions that underlie the...Ch. 25 - Prob. 17CONQCh. 25 - What is a prion? Explain how a prion relies on...Ch. 25 - 19. Some people have a genetic predisposition for...Ch. 25 - What is the difference between an oncogene and a...Ch. 25 - Prob. 21CONQCh. 25 - Prob. 22CONQCh. 25 - Prob. 23CONQCh. 25 - Prob. 24CONQCh. 25 - Prob. 25CONQCh. 25 - Prob. 26CONQCh. 25 - Prob. 27CONQCh. 25 - With regard to cancer cells, which of the...Ch. 25 - Prob. 29CONQCh. 25 - 1. Which of the following experimental...Ch. 25 - Prob. 2EQCh. 25 - 3. What is meant by the term genetic testing? How...Ch. 25 - Prob. 4EQCh. 25 - 5. Chapter 21 describes a method known as Western...Ch. 25 - 6. An experimental assay for the blood-clotting...Ch. 25 - 7. Discuss ways to distinguish whether a...Ch. 25 - 8. The codon change (Gly-12 to Val-12) in...Ch. 25 - Explain how DNA microarrays are used in molecular...Ch. 25 - Make a list of the benefits that may arise from...Ch. 25 - 2. Our government has finite funds to devote to...Ch. 25 - Prob. 3QSDC
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- Color blindness in men is controlled by a recessive gene located on the X chromosome. Can a brother and sister with color blindness have another normal brother? A. Yes, if the mother is a carrier. B.Yes, if the mother is homozygous. C.Yes, if the father is heterogametic. D.Yes, if the father is a carrier.arrow_forwardHemophilia in humans is due to a mutation on the X chromosome. What will be the result of mating between a normal (non-carrier) female and a hemophiliac male? A. Half of the daughters are normal and half of the sons are hemophiliacs. B. All sons are normal and all daughters are carriers. C. All daughters are normal and all sons are carriers. D. Half of the children are normal and the other half are hemophiliacs; All daughters are carriers.arrow_forwardNondisjunction can happen in males and females. It has been found to correlate with advanced maternal age but not paternal age. Why is that? A. Because estrogen promotes non-disjunction. B. Because oogenesis has a prolonged prophase and is more prone to have errors with maternal age. C. Because more mutations can happen in females. D. All of the above.arrow_forward
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- Which observation led Thomas Morgan to realize that the gene for fruit fly eye color was located on a sex chromosome? a. He noticed that only male F2 flies could have white eyes; no females displayed this trait. b. He saw that the F2 generation of flies had the classic 3:1 phenotypic ratio of red eyes to white eyes c. He read it in a biology textbook d. He noticed that only mutant flies had white eyesarrow_forwardHow is this trait inherited? A. The trait is epistatic. B. The trait is X-linked. C. The trait is dominant. D. The trait is recessive.arrow_forwardWhich of the following best describes Klinefelter syndrome? A. It is an example of aneuploidy. B. Affected individuals are males with low fertility. C. Only one X chromosome is active in these individuals. D. All of the above.arrow_forward
- What is the main difference between autopolyploid and allopolyploid? a. the number of chromosomes b. the functionality of the chromosomes c. the source of the extra chromosomes d. the number of mutations in the extra chromosomesarrow_forwardWhich of the following statements regarding the Y chromosome in mammals is TRUE?A. The Y chromosome is less than half the size of the X chromosome.B.Y chromosomes are most often present in egg cells and are not found in sperm cells. C.Most female mammals have one Y chromosome. D. The Y chromosome contains no protein-coding genes.arrow_forwardIn diseases with a recessive inheritance linked to sex (X chromosome), from the mother: A. 50% of women and 50% of men are affected. B. The woman is always affected by the disease. C. The man is always affected by the disease. D. 50% of women are affected.arrow_forward
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