EBK CONCEPTS OF GENETICS
12th Edition
ISBN: 9780134818979
Author: Killian
Publisher: YUZU
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Textbook Question
Chapter 26, Problem 13PDQ
Assume that a recessive autosomal disorder occurs in 1 of 10,000 individuals (0.0001) in the general population and that in this population about 2 percent (0.02) of the individuals are carriers for the disorder. Estimate the probability of this disorder occurring in the offspring of a marriage between first cousins. Compare this probability to the population at large.
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Check out a sample textbook solutionStudents have asked these similar questions
A given autosomal locus has three possible alleles (A1, A2, and A3). Assuming that the numbers of individuals with the six possible genotypes are as follows, what would be the frequency of the A1 allele in the population?
A1A1 = 30 A1A2 = 27 A2A2 = 12
A1A3 = 17 A2A3 = 10 A3A3 = 4
What would be the frequency of the A3A3 genotype? Assume the population is under Hardy-Weinberg equilibrium.
A.
0.182
B.
0.27
C.
0.03
D.
0.317
E.
0.107
F.
0.09
Assume that the frequency of an allele that causes an autosomal recessive disease is 0.03. What is the probability of a person having the disease when his or her parents are unrelated (i.e., mating is random)? What is the probability of having the disease when the parents are first cousins? What about when the parents are second cousins?
The incidence of a rare autosomal recessive genetic disorder, Tay-Sachs, is approximately 1 in
3,500 in a certain population. Assuming that this population is in Hardy-Weinberg equilibrium,
what is the probability that a phenotypically normal female with no family history, and a
phenotypically normal male who had an affected great-aunt, will have a child who is a carrier for
Tay-Sachs?
Chapter 26 Solutions
EBK CONCEPTS OF GENETICS
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