Major histocompatibility complex is the group of genes that encode for proteins that are crucial for antigen presentation. This MHC gene is located on chromosome 6 and code for MHC protein. MHC proteins are classified into two classes MHC I and MHC II, these cell surface proteins recognize and bind with antigens from pathogens and present them to immune cells. MHCs regulate adaptive immune response.
The MHC proteins are called as human leukocyte antigens (HLAs) in case of humans. These proteins are responsible for antigen presentation to the T cell receptors. T cell receptors are formed by combination of three different complementarity determining regions CDR (1, 2 and 3).
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