Organic Chemistry
Organic Chemistry
9th Edition
ISBN: 9781305080485
Author: John E. McMurry
Publisher: Cengage Learning
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Chapter 29.SE, Problem 53AP
Interpretation Introduction

Interpretation:

To show the mechanism of the reaction when conversion of two molecules of acetyl CoA to one molecule of acetoacetyl CoA, is a Claisen reaction.

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Acyl-CoA synthase is the enzyme that activates a fatty acid by converting it to a fatty acyl-CoA in a series of two reactions. In the first reaction, the fatty acid reacts with ATP and one of the products formed is ADP. The other product reacts in a second reaction with CoASH to form the fatty acyl-CoA. Propose a mechanism for each of the reactions.
If you start with acetyl-CoA labeled with 14C in the methyl-carbon, where does the label end up in malonyl-CoA? Support your answer by drawing conversion reaction of acetyl-CoA coversion to Malonyl-CoA.
draw the chemical structures of the reactant and product of the following reactions: a.) addition of a phosphate group to (ex: phosphorylation of) glycose b.) addition of a phosphate group to (ex: phosphorylation of) fructose-6-phosphate c.) addition of a phosphate group to (ex: phosphorylation of) phosphoenolpyruvate

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