Essentials of Genetics
9th Edition
ISBN: 9781292108933
Author: KLUG
Publisher: PEARSON
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Chapter 3, Problem 5PDQ
When working out genetics problems in this and succeeding chapters, alwaysassumethatmembersof the P1 generation are homozygous, unless the information or data you are given require you to do otherwise.
In a problem involving albinism (see Problem 4), which of Mendel's postulates are demonstrated?
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Unpacking the Problem 44John and Martha are contemplating having children, butJohn’s brother has galactosemia (an autosomal recessivedisease) and Martha’s great-grandmother also had galactosemia. Martha has a sister who has three children, none ofwhom have galactosemia. What is the probability that Johnand Martha’s first child will have galactosemia?1. Can the problem be restated as a pedigree? If so, writeone.2. Can parts of the problem be restated by using Punnettsquares?3. Can parts of the problem be restated by using branchdiagrams?4. In the pedigree, identify a mating that illustratesMendel’s first law.5. Define all the scientific terms in the problem, and lookup any other terms about which you are uncertain.6. What assumptions need to be made in answering thisproblem?7. Which unmentioned family members must be considered? Why?8. What statistical rules might be relevant, and in whatsituations can they be applied? Do such situations existin this problem?9. What are two generalities…
Question:
Suppose the progeny were crossed. Fill in the Punnett Squares below and answer the following questions.
Seed Color
Seed Shape
R
r
A
a
In a pea plant experiment, the allele (R) producing yellow seed color is dominant, and the allele (r) producing green seed color is recessive. A homozygous recessive genotype would produce green seeds. Similarly, the allele (A) producing round seed shape is dominant to the allele (a) that produces wrinkled seed shape. A homozygous recessive genotype would produce wrinkled seeds. Both traits sort independently of each other.
Given a pure-breeding cross between a round, green pea plant and a wrinkled yellow plant, complete the rest of the Punnett Squares below, and answer the following questions.
R
R
A
A
RA
Ra
Ra
ra
Question: This is a normal 3 point test cross, except that instead of regular phenotypes, you are looking at DNA markers on a gel. One parent, according to the gel, is heterozygous at each marker. The other parent is homozygous for each marker. (Again, this means it is a test cross: AaEeHh x AAEEHH --but don't be confused by that, because these are not "dominant" and "recessive" per se; the phenotype is just a band on a gel). For each offspring, figure out its genotype (homozygous or heterozygous for each gene. Then, figure that one parent made only AEH gametes, so you can cross that out if it helps.) Then treat it pretty much the same as a 3 point test cross.
Chapter 3 Solutions
Essentials of Genetics
Ch. 3 -
CASE STUDY | To test or not to test
Thomas...Ch. 3 -
CASE STUDY | To test or not to test
Thomas...Ch. 3 - CASE STUDY | To test or not to test Thomas first...Ch. 3 -
CASE STUDY | To test or not to test
Thomas...Ch. 3 - When working out genetics problems in this and...Ch. 3 - When working out genetics problems in this and...Ch. 3 - When working out genetics problems in this and...Ch. 3 -
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When working out genetics problems in this and...
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- Solving complex genetic problems with the rules of probability (3 traits) 1. Calculate the probability of getting an offspring of pea plant with the genotype, PpyyRr, when crossing PpYyRr and ppyyrr. Show your work. 2. States the phenotypes of the parents and offspring.arrow_forwardAnalysis of Autosomal Recessive and Dominant Traits In the following pedigree, assume that the father of the proband is homozygous for a rare trait. What pattern of inheritance is consistent with this pedigree? In particular, explain the phenotype of the proband.arrow_forwardKeeping it in the family!”- How do you think consanguinity is increasing the risk factors of genetic disorders? Explain with examples (at least two). It won’t be possible to change the tradition all of a sudden. If you are a clinical geneticist, how you will be managing this type of community?arrow_forward
- pls dont copy existing answers or i will dislike your answer thanks Phenylketonuria (PKU) is a disorder caused by a recessive allele. Two carrier individuals have progeny. Answer the following questions in order and show solutions whenever relevant. 1. If they have a normal child, what is the probability that he or she will be heterozygous? 2. If they have three children, what is the probability of having 2 affected children and one normal child?arrow_forwardGENETICS Question; 1. Give the genotypes and its ratio of the dihybrid cross of FIGURE 7. Regarding this problem, you may refer the genotype of the monohybrid cross of pea flower color in Figure 6.arrow_forwardThe 6 genetic inheritance patterns that do not follow Mendel’s Laws.arrow_forward
- Analysis of X-Linked Dominant and Recessive Traits Suppose a couple, both phenotypically normal, have two children: one unaffected daughter and one son affected with a genetic disorder. The phenotype ratio is 1:1, making it difficult to determine whether the trait is autosomal or X-linked. With your knowledge of genetics, what are the genotypes of the parents and children in the autosomal case? In the X-linked case?arrow_forwardTrue or false? All traits are inherited in a Mendelianpattern.arrow_forwardQUESTION 5. The pedigree below follows the appearance of a rare autosomal dominant condition resulting in malformation of limbs through a family. What is the penetrance of this trait? i.e., What is the ratio between the number of individuals in the pedigree who display the trait (numerator) and the number of individuals you know from the pedigree must have the trait-determining genotype (denominator)? Enter your answer in the form of a fraction without any spaces. e.g., If your answer is “one-fourth”, enter: 1/4arrow_forward
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