Concept explainers
To explain:
The enzymatic reaction involving pyruvate dehydrogenase in the intermediate stage – the place where it occurs, if the process needs oxygen.
Concept introduction:
Glycolysis is the first step of
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- Identify where sugar oxidation, substrate-level phosphorylation, and the reduction of NAS+ occurs in glycolysisarrow_forwarddescribe how the pyruvate dehydrogenase complex is regulated?arrow_forwardGive the Steps, Enzyme/s involved, Electron carriers, ATP Generation, End product and significance of the following metabolic pathway: Pyruvate Oxidation (explain in 1-3 sentences only)arrow_forward
- Identify the means by which the pyruvate dehydrogenase complex is regulated.arrow_forwardWhich one of the five steps of the pyruvate dehydrogenase complex reaction is most likely to be metabolically irreversible? Explain.arrow_forwardExplain why rotenone inhibits oxidative phosphorylationwhen the substrate is pyruvate, but not when succinate isusedarrow_forward
- Explain why the use of the ATP analog below in the reaction catalyzed by pyruvate carboxylase might lead to a carboxylated ATP derivative rather than the normal product oxaloacetatearrow_forwardExplain substrate cycling in glycolysis in relation to gluconeogesisarrow_forwardIdentify all of the inputs and outputs for glycolysis, krebs cycle, and oxidative phosphorylation. What are the regulatory steps of these pathways and what do the key regulatory enzymes control? What compounds inhibit/activate these enzymes?arrow_forward
- BiochemistryBiochemistryISBN:9781305577206Author:Reginald H. Garrett, Charles M. GrishamPublisher:Cengage Learning