Human Physiology
Human Physiology
15th Edition
ISBN: 9781259864629
Author: Fox, Stuart Ira
Publisher: Mcgraw-hill Education,
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Chapter 4, Problem 5cCP
Summary Introduction

To review:

The effect of a defective enzyme on the concentration of the intermediates in a pathway. 

Introduction:

The mechanism of end-product inhibition is used for controlling the amount of product formed in a reaction. During this inhibition, the final product inhibits the activity of an enzyme involved in initiation of the formation of this end-product. End-product inhibition occurs in order to prevent the accumulation of the final product.

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Students have asked these similar questions
Because of an inborn error of metabolism, suppose that the enzyme that catalyzed the third reaction in your pathway (see no. 5a) was defective. Describe the effects this wouldhave on the concentrations of the intermediates in your pathway.
Why does metabolism not grind to a halt when an endergonic reaction occurs within a pathway?
Give the two reasons why anabolic reactions in metabolism are not exactly the reverse of catabolic pathway.

Chapter 4 Solutions

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