Biological Science (7th Edition)
7th Edition
ISBN: 9780134678320
Author: Scott Freeman, Kim Quillin, Lizabeth Allison, Michael Black, Greg Podgorski, Emily Taylor, Jeff Carmichael
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Question
Chapter 43, Problem 12PIAT
Summary Introduction
To review:
The research technique that could be used to discover the effect of BTX (batrachotoxin) on specific membrane proteins, and the result of the technique on the basis of the given graph.
Introduction:
The BTX is a milky compound that is highly toxic in nature and is secreted from the skin of some frog species. It opens the sodium channel and causes membrane depolarization. The graph showing the effect of BTX on the membrane potential of a squid giant axon is given below:
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Describe an additional experimental approach used to study the cytoskeleton in which the activity of cytoskeletal elements is affected in ways similar to those resulting from drug treatment.
Cellular reprogramming and induced pluripotent stem cells have allowed scientists to model various diseases and screen drugs in these in vitro models. Please select a disease (like cancer) that can be modeled through the generation of induced pluripotent stem cells. You can use published literature and explain:1) why is it important to model such a disease?2) what were the key findings after modeling such a disease? 3) a drug that has been screened in this disease model. Explain in detail the main findings.
You are interested in the mobility of two different unknown integral plasma membrane proteins—protein X and protein Y—in a cell. In one cell, you fluorescently label all the X proteins. In another cell, you label all the Y proteins. When you perform FRAP analysis on both cells, you find that most of the protein X fluorescence has recovered within 3 minutes, but recovery of the protein Y fluorescence is significantly slower. Even after 10 minutes, only 50% of the protein Y fluorescence has recovered. Describe the FRAP experimental protocol, explain what the results tell you about mobility of the X and Y proteins, and propose a possible explanation for why the mobilities of the two proteins differ.
Chapter 43 Solutions
Biological Science (7th Edition)
Ch. 43 - In a neuron, what creates the electrochemical...Ch. 43 - Prob. 4TYKCh. 43 - Explain the difference between a ligand-gated K+...Ch. 43 - Prob. 6TYUCh. 43 - Prob. 7TYUCh. 43 - Prob. 8TYUCh. 43 - Prob. 9TYPSSCh. 43 - Alzheimer’s disease is a common form of dementia...Ch. 43 - Prob. 11PIATCh. 43 - Prob. 12PIAT
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- You have isolated a new species of infectious bacteria. The bacterium releases a toxin that you believe is adversely affecting heterotrimeric Gs (stimulatory)-protein-based signaling. To explore this hypothesis you use an epithelial cell line that is expressing a cyan fluorescent protein (CFP)-labeled α subunit and a yellow fluorescent protein (YFP)-labeled β subunit of a heterotrimeric Gs-protein. CFP emits blue light and has excitation and emission wavelengths of 440 nm and 490 nm, respectively. YFP emits yellow light and has excitation and emission wavelengths of 490 nm and 527 nm, respectively. To test your hypothesis, you perform two experiments. First, you apply a signaling ligand known to activate this Gs protein and track yellow fluorescence. Second, you apply the signaling ligand and the purified bacterial toxin simultaneously and track yellow fluorescence. Which of the following conclusion will you draw based on the above experimental data? The toxin locks the α subunit…arrow_forwardCancer stem cells (CSCs) are cancer cells (found within tumors or hematological cancers) that possess characteristics associated with normal stem cells, specifically the ability to give rise to all cell types found in a particular cancer sample. There are many biomedical engineering based approaches to detect CSCs. Question: What kind of systems have been developed to detect CSCs? Describe by giving examples. Please explain in detail the main findings with your own words.arrow_forwardDraw a pair of antiparallel microtubules across the page. The following should be clarified or added: a. plus and minus ends clearly denoted on both microtubules b. the fact that each microtubule is a polymer of alpha+beta heterodimers must be denoted (with correct orientation) c. one microtubule is bound by a simple representation of plus-end directed motor protein. The motor protein should be named and representation indicates which direction it moves. d. one microtubule is bound by a simple representation of minus-end directed motor protein. The motor protein should be named and representation indicates which direction it moves.arrow_forward
- Cancer stem cells (CSCs) are cancer cells (found within tumors or hematological cancers) that possess characteristics associated with normal stem cells, specifically the ability to give rise to all cell types found in a particular cancer sample. There are many biomedical engineering based approaches to detect CSCs. Question: What kind of systems have been developed to detect CSCs? Describe by giving examples. Please explain with a few examples.arrow_forwardCancer stem cells (CSCs) are cancer cells (found within tumors or hematological cancers) that possess characteristics associated with normal stem cells, specifically the ability to give rise to all cell types found in a particular cancer sample. There are many biomedical engineering based approaches to detect CSCs. Question: What kind of systems have been developed to detect CSCs? Describe by giving examples. Thank you.arrow_forwardCancer stem cells (CSCs) are cancer cells (found within tumors or hematological cancers) that possess characteristics associated with normal stem cells, specifically the ability to give rise to all cell types found in a particular cancer sample. There are many biomedical engineering based approaches to detect CSCs. Question: What is the importance and advanatge of detecting CSCs? Please explain in detailarrow_forward
- For this exercise, an electron micrograph of secretory cells of the anterior pituitary is being used (Sandborn, E.B. (1970) Cells and Tissues by Light and Electron Microscopy, New York, New York: Academic Press, Inc.). The image originally measured 18.7 cm wide and 18.5 cm high with a magnification of 5200x. Given the width of the original micrograph at 18.7cm, what is the true width of unmagnified image? Show calculations.arrow_forwardCancer stem cells (CSCs) are cancer cells (found within tumors or hematological cancers) that possess characteristics associated with normal stem cells, specifically the ability to give rise to all cell types found in a particular cancer sample. There are many biomedical engineering based approaches to detect CSCs. Question: What is the importance and advanatge of detecting CSCs? Please explain in detail the main findings with your own words.arrow_forwardName and define (briefly) the four different types of receptors involved in Cellsignaling. Give an example of a ligand and specific type of receptor (where would you find the receptor?) for one of the receptors defined.arrow_forward
- Protein transfer to a membrane from a developed electrophoretic gel can be performed under which of the following conditions?arrow_forwardCancer stem cells (CSCs) are cancer cells (found within tumors or hematological cancers) that possess characteristics associated with normal stem cells, specifically the ability to give rise to all cell types found in a particular cancer sample. There are many biomedical engineering based approaches to detect CSCs. Question: What is the importance and advanatge of detecting CSCs? Thank you.arrow_forwardIn the lab you will prepare a dye solution to test transmembrane transport into yeast cells. The dye stock solution has a concentration of 5 mM. For your experiment, you want the dye concentration to be at 0.25 mM. You do the dilution with water. Select among the following, which of the following method(s) will give you the correct final concentration of dye? 1) adding 1 ml of stock solution to 19 ml of water. 2) making a 25-fold dilution. 3) adding 100 ml of water to 5 ml of dye stock solution. 4) diluting 3 ml of concentrated dye with water to a final volume of 60 ml. A. All methods are accurate B. only methods 1, 2 and 3 are accurate C. only methods 1, 3 and 4 are accurate D. only methods 1 and 4 are accurate E. only method 3 is accurate F. None of the methods reflect the proper dilution method.(edited) [3:16 PM]arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSON
Biology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStax
Anatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education
The Cell Membrane; Author: The Organic Chemistry Tutor;https://www.youtube.com/watch?v=AsffT7XIXbA;License: Standard youtube license