Biological Science (7th Edition)
7th Edition
ISBN: 9780134678320
Author: Scott Freeman, Kim Quillin, Lizabeth Allison, Michael Black, Greg Podgorski, Emily Taylor, Jeff Carmichael
Publisher: PEARSON
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Chapter 43, Problem 5TYU
Explain the difference between a ligand-gated K+ channel and a voltage-gated K+ channel.
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Separately, draw a table using arrows to depict the appropriate magnitude and direction of the forces and ion fluxes at different membrane potentials for a ligand-gated channel that is equally permeable to both ion X+ and ion Y+. The equilibrium potential for ion X+ is -60 mV, and the equilibrium potential for ion Y+ is -20 mV. Which item (a, b, c, or d) best represents the forces and fluxes for a membrane potential of +20 mV? Upwards arrows means outward direction and downwards arrow means inward direction. The length of the arrow determines the magnitude.
Separately, draw a table using arrows to depict the appropriate magnitude and direction of the forces and ion fluxes at different membrane potentials for a ligand-gated channel that is equally permeable to both ion X+ and ion Y+. The equilibrium potential for ion X+ is -60 mV, and the equilibrium potential for ion Y+ is -20 mV.
Which item best represents the forces and fluxes for a membrane potential of 0 mV?
Distinguish between a pump and a channel, and describe the three specific states of a voltage- gated Na+ channel.
Chapter 43 Solutions
Biological Science (7th Edition)
Ch. 43 - In a neuron, what creates the electrochemical...Ch. 43 - Prob. 4TYKCh. 43 - Explain the difference between a ligand-gated K+...Ch. 43 - Prob. 6TYUCh. 43 - Prob. 7TYUCh. 43 - Prob. 8TYUCh. 43 - Prob. 9TYPSSCh. 43 - Alzheimer’s disease is a common form of dementia...Ch. 43 - Prob. 11PIATCh. 43 - Prob. 12PIAT
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- Conformational changes in channel proteins brought about by voltage changes are responsible for opening and closing Na+ and K+ gates during the generation of an action potential. (True or false?)arrow_forwardname the three ways in which an ion channel can be gated.arrow_forwardExplain how the crystal structures of potassium ion channels suggest the way in which the voltage-sensing domains interact with other parts of the proteins to open and close the ion channels. How does this structure-function relationship apply to other voltage-gated ion channels?arrow_forward
- What is the difference between a ligand-gated channel (like H1 or the AChR) and a voltage gated channel?arrow_forwardSeparately, draw a table using arrows to depict the appropriate magnitude and direction of the forces and ion fluxes at different membrane potentials for a ligand-gated channel that is equally permeable to both ion X+ and ion Y+. The equilibrium potential for ion X+ is -60 mV, and the equilibrium potential for ion Y+ is -20 mV. Which item best represents the forces and fluxes for a membrane potential of -60 mV? Pick one of the four tables in the included image please for your answer.arrow_forwardDefine the term ligand-gated ion channels?arrow_forward
- Define the term voltage-gated ion channels?arrow_forwardWhich of the following statements best describes the features of voltage-gated K+ channels? They consist of 4 subunits, are activated at the same time as voltage-gated Na+ channels, but do not inactivate. They consist of 4 subunits, are activated by depolarisation and close slowly during the refractory period. They have 24 membrane spanning alpha helices, 4 of which have positively charged amino acids which promote a conformational change in the channel following depolarisation. They consist of 4 subunits and are open at rest which causes the resting membrane potential to be close to the K+ equilibrium potential.arrow_forwardexplain the difference between a ligand gated and voltage gated ion channelarrow_forward
- DESCRIBE THE MECHANISM FOR FAST LIGAND-GATED CHANNELS AND THE TYPES OF CHANGES THEY CAN PRODUCE IN THE CELL MEMBRANE.arrow_forwardDescribe the contribution of each of the following to the establishment and maintenance of membrane potential: Part A Na+K+ Pump Passive movement of K+ across the membrane Passive movement of Na+ across the membranearrow_forwardWhich of the following statements about voltage gated channels is true? Voltage-gated sodium channels open at a higher (more positive) membrane potential than do potassium-gated channels Voltage-gated sodium channels open at a lower (more negative) membrane potential than do potassium-gated channels Sodium- and postassium-gated channels open at about the same membrane potential, but they have different effects because there are different numbers of the two kinds of channels in neuron cell membranesarrow_forward
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