Concept explainers
Interpretation: The stereogenic centers in the given compound are to be located. Each stereogenic center is to be labeled as
Concept introduction: An atom bearing four different atoms or groups which produces stereoisomers on interchange of any two groups are stereogenic centers.
The stereogenic centers with
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- The R-S Convention 14) Either the letter R (rectus, or right) or S (sinister, or left) is used to designate the configuration at a stereogenic center. The four atoms or groups attached to the stereogenic center are arranged in a priority order according to atomic number: the higher the atomic number, the higher the priority (see Cahn-Ingold-Prelog rules for assigning priorities). If two atoms have the same atomic number, we move to the next atoms out from the stereogenic center, or even further, until we observe a difference in atomic number. We then view the molecule from the side opposite the group with the lowest priority. If the remaining three groups in order from highest to lowest priority form a clockwise array, the configuration is R; if counterclockwise, the configuration is S. a)Construct a model of 2-chlorobutane. Which carbon in the chain is a stereogenic center? b)What are the four groups attached to this stereogenic center? c)Which group has the highest…arrow_forwardRank the following groups in order of decreasing priority. −NH2, −CH2NH2, −CH3, −CH2NHCH3arrow_forwardDraw and name the seven aldehydes and ketones with the formula C5H10O. Which are chiral?arrow_forward
- Rank the following groups in order of decreasing priority. −CH=CH2, −CH3, −C≡CH, −Harrow_forwardWhich of the following Newman projections are representations of R-2-butanol?arrow_forwardHi, could someone show me how to draw the Newman Projection for C2-C3 bond of 2,2-dimethylbutane and tell me which one is stable using steric and torsional strain? I’m not sure how to do this and it’s confusing. Thanks!arrow_forward
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- Rank the following groups in order of decreasing priority. a. – COOH, – H, – NH2, – OH b. – H, – CH3, – Cl, – CH2CI c. -CH2CH3, -CH3, -H, -CH(CH3)2 d. – CH = CH2, – CH3, – C ≡ CH, – Harrow_forwardDraw and name all stereoisomers of 3-methyl-2,4-hexadiene, using E-Z nomenclature.arrow_forwardThe Ka1 of ascorbic acid is 7.94 x 10-5. Would you expect ascorbic acid dissolved in blood plasma (pH 7.35–7.45) to exist primarily as ascorbic acid or as ascorbate anion? Explain.arrow_forward
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