Biology: The Dynamic Science (MindTap Course List)
Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN: 9781305389892
Author: Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher: Cengage Learning
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Chapter 7, Problem 14TYK

Apply Evolutionary Thinking Which of the two phosphorylation mechanisms, oxidative phosphorylation or substrate-level phosphorylation, is likely to have appeared first in evolution? Why?

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What is substrate-level phosphorylation and electron transfer phosphorylation? Compare and contrast the two. (hint: what is phosphorylation)
(Biochemistry topics: Glycolysis, Citric Acid Cycle, and Electron Transport.)  There is a reciprocal regulation of glycolytic and gluconeogenic reactions interconverting fructose-6-phosphate and fructose-1,6-biphosphate. Which one of the following statements about this regulation is not correct? This regulation allows control of the direction of net metabolite flow through the pathway. Fructose-2,6- bisphosphate activates phosphofructokinase-1. Fructose-2,6-biphosphate inhibits fructose-1,6-bisphosphate. The fructose-1,6-bisphosphatase reaction is exergonic.  The PFK1 reaction is exergonic.
You have discovered a protein that is able to add a phosphate to ADP without the help of a proton gradient. As a result you know a. this is an example of substrate level phosphorylation. b. this must be a mutant protein as ATP is only made by ATP synthase in the mitochondria. c. this protein must be found in plants only. d. this protein would be found in Complex I of the electronic transport chain (ETC). e. the action of this protein is known as oxidative phosphorylation.
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