Genetic Analysis: An Integrated Approach (3rd Edition)
3rd Edition
ISBN: 9780134605173
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 7, Problem 37P
The following diagram shows the parental strands of a DNA molecule undergoing replication. Draw the daughter strands present in the replication bubble, indicating
a. the polarity of daughter strands
b. the leading and lagging strands
c. Okazaki fragments
d. the location of RNA primers
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The following diagram represents a DNA molecule that is undergoing replication. Draw in the strands of newly synthesized DNA and identify (a) the polarity of the newly synthesized strands, (b) the leading and lagging strands, (c) Okazaki fragments, and (d) RNA primers.
During DNA replication, the helicase enzyme binds to DNA and
Select one:
a. prevents the DNA strands from rewinding back into the helical shape
b. cuts the double stranded DNA into single strands
c. provides the starting point where new nucleotides can be added
d. adds new nucleotides to the template strand
A drug that inhibits the DNAa protein is added to a culture of E. coli cells. What is the first step of DNA replication that will be impaired by this drug?
PICK ONE ANSWER:
A. Keeping parent DNA strands separated
B. Releasing tension generated by supercoiling
C. Activating the origin of replication
D. Making primers
E. Forming phosphodiester bonds
Chapter 7 Solutions
Genetic Analysis: An Integrated Approach (3rd Edition)
Ch. 7 - What results from the experiments of Frederick...Ch. 7 - 7.2 Explain why Avery, MacLeod, and McCarty’s in...Ch. 7 - 7.3 Hershey and Chase selected the bacteriophage...Ch. 7 - 7.4 Explain how the Hershey and Chase experiment...Ch. 7 - 7.5 One strand of a fragment of duplex DNA has the...Ch. 7 - 7.6 The principles of complementary base pairing...Ch. 7 - For the following fragment of DNA, determine the...Ch. 7 - 7.8 Figures present simplified depictions of...Ch. 7 - 7.9 Consider the sequence -ACGCTACGTC-.
What is...Ch. 7 - DNA polymerase III is the main DNA-synthesizing...
Ch. 7 - There is a problem completing the replication of...Ch. 7 - Explain how RNA participates in DNA replication.Ch. 7 - A sample of double-stranded DNA is found to...Ch. 7 - Bacterial DNA polymerase I and DNA polymerase III...Ch. 7 - Diagram a replication fork in bacterial DNA and...Ch. 7 - Prob. 16PCh. 7 - Which of the following equalities is not true for...Ch. 7 - List the order in which the following proteins and...Ch. 7 - Two viral genomes are sequenced, and the following...Ch. 7 - Matthew Meselson and Franklin Stahl demonstrated...Ch. 7 - Raymond Rodriguez and colleagues demonstrated...Ch. 7 - 7.22 Joel Huberman and Arthur Riggs used pulse...Ch. 7 - 7.23 Why do the genomes of eukaryotes, such as...Ch. 7 - Bloom syndrome (OMIM 210900) is an autosomal...Ch. 7 - 7.25 How does rolling circle replication (see...Ch. 7 - Telomeres are found at the ends of eukaryotic...Ch. 7 - A family consisting of a mother (I-1), a father...Ch. 7 - In a dideoxy DNA sequencing experiment, four...Ch. 7 - Prob. 29PCh. 7 - Using an illustration style and labeling similar...Ch. 7 - A PCR reaction begins with one double-stranded...Ch. 7 - Prob. 32PCh. 7 - Prob. 33PCh. 7 - 7.34 A sufficient amount of a small DNA fragment...Ch. 7 - You are participating in a study group preparing...Ch. 7 - Prob. 36PCh. 7 - The following diagram shows the parental strands...Ch. 7 - Go to the OMIM website...
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- The following diagrams represent DNA molecules that are undergoing replication. Draw in the strands of newly synthesized DNA and identify (a) the polarity of the newly synthesized strands, (b) the leading and lagging strands, (c) Okazaki fragments, and (d) RNA primers.arrow_forwardThe diagram shows a model of DNA replication. The diagram points out a number of enzymes and protein factors involved in the process. If this cell were cancerous, a doctor might be using a chemotherapy drug to prevent the replication process from taking place. One such drug, topotecan, inhibits the topoisomerase enzyme from working. Based on the model, if topotecan is used, how will this affect the replication process? A: The hydrogen bonds between the bases will not break B: The double helix of the DNA molecule will not unwind C: It will prevent the addition if complementary nitrogen bases to the leading or lagging DNA strands D: It will prevent the addition of nitrogen bases due to instability of the single-stranded DNA chainsarrow_forwardWhat is the function of Ligase during DNA Replication a Releases tension on the DNA as it unwinds b Puts down RNA primers so replication can continue c Binds Okazaki Fragments into a continuous DNA strand d Binds to single stranded DNA to protect it from degradationarrow_forward
- In DNA replication, a primer is _____. a. what the original DNA strands are called b. a molecule that provides the energy for nucleotide attachments c. a regulatory protein that turns on the gene that starts DNA replication d. an enzyme that breaks the hydrogen bonds between base pairs e. a short piece of nucleic acid that serves as an attachment point for DNA polymerasearrow_forwardWhy is DNA replication called semiconservative? A. Both daughter strands are entirely new B. Each daughter duplex contains one strand from the parent structure and one new strand C. Each daughter duplex will contain parts of the parental strand in each strand. D. None of these is the correct answer.arrow_forwardWhat is the major role of DNA polymerase in the DNA replication? a. Attached RNA primers to initiate the addition of complementary nucleotide sequence at the 5’ to 3’direction b. Adds up new complementary nucleotide sequence at the 3’ to 5’ direction of the DNA template. c. Unwinds the double helix by breaking the bonds at the 3’ to 5’ polymerization activity. d.It transiently cuts each strand to prevent supercoil at the 5’ to 3’ polymerization activity complementary to the RNA strandarrow_forward
- In DNA replication, the role of topoisomerase is to Question 11 options: a) "unzip" the double stranded DNA in front of DNA polymerase. b) maintain the single stranded DNA. c) supercoil the DNA after the replication fork has passed. d) relieve supercoil tension in the DNA in front of the replication fork.arrow_forwardDiscontinuous replication is a result of which property of DNA? a. Complementary bases b. Charged phosphate group c. Antiparallel nucleotide strands d. Five-carbon sugararrow_forwardWhat is DNA polymerase? a.An enzyme that carries out DNA replication b.Short, single strand of DNA that base-pairs with a specific DNA sequence c.An enzyme that corrects mutations that arise during the replication of DNA d.An enzyme that seals any gaps that remain between bases of replicating strands of DNAarrow_forward
- Successful bacterial DNA replication does NOT … please explain the answer choice a.ligate DNA nicks b.use a bidirectional fork c.prime new synthesis using DNA primers d.have SSB (single strand binding protein) stabilize single stranded DNAarrow_forwardDNA polymerase III is a processive enzyme, which means that a. it does not dissociate from the growing strand after it has attached a nucleotide to the 3′ end. b. it makes a new strand very quickly. c. it proceeds toward the opening of the replication fork. d. it copies DNA with relatively few errors.arrow_forwardWhy is DNA replication considered semiconservative? A. Both strands of each replicating DNA molecules are conserved. B. One molecule consists of the old strands and the other DNA molecule is entirely new. C. One strand of each replicating DNA molecule is conserved and the other strand is newly synthesized. D. Both strands of each replicating DNA molecule are new.arrow_forward
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