WebAssign for Rosner's Fundamentals of Biostatistics, 8th Edition [Instant Access], Single-Term
WebAssign for Rosner's Fundamentals of Biostatistics, 8th Edition [Instant Access], Single-Term
8th Edition
ISBN: 9780357452905
Author: Rosner
Publisher: Cengage Learning US
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Chapter 7, Problem 69P

The combination of photochemotherapy with oral methoxsalen (psoralen) and ultraviolet A radiation (called PUVA treatment) is an effective treatment for psoriasis. However, PUVA is mutagenic, increases the risk of squamous-cell skin cancer. and can cause irregular, pigmented skin lesions. Stern et al. [4] performed a study to assess the incidence of melanoma among patients treated with PUVA. The study identified 1380 patients with psoriasis who were first treated with PUVA in 1975 or 1976. Patients were subdivided according to the total number of treatments received (<250 or >250 from 1975 to 1996). Within each group, the observed number of melanomas was determined from 1975 to 1996 and compared with the expected number of melanomas as determined by published U.S. age- and gender-specific melanoma incidence rates. The results were as in Table 7.8.

Chapter 7, Problem 69P, The combination of photochemotherapy with oral methoxsalen (psoralen) and ultraviolet A radiation

Suppose we want to compare the observed and expected number of events among the group with <250 treatments. Perform an appropriate significance test, and report a two-tailed p-value.

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Chapter 7 Solutions

WebAssign for Rosner's Fundamentals of Biostatistics, 8th Edition [Instant Access], Single-Term

Ch. 7 - The mean serum-creatinine level measured in 12...Ch. 7 - The mean serum-creatinine level measured in 12...Ch. 7 - The mean serum-creatinine level measured in 1 2...Ch. 7 - The mean serum-creatinine level measured in 12...Ch. 7 - The mean serum-creatinine level measured in 12...Ch. 7 - The mean serumcreatinine level measured in 12...Ch. 7 - The mean serumcreatinine level measured in 12...Ch. 7 - Plasma-glucose levels are used to determine the...Ch. 7 - Plasma-glucose levels are used to determine the...Ch. 7 - Plasma-glucose levels are used to determine the...Ch. 7 - Suppose the incidence rate of myocardial...Ch. 7 - Suppose the incidence rate of myocardial...Ch. 7 - Suppose the incidence rate of myocardial...Ch. 7 - Suppose the incidence rate of myocardial...Ch. 7 - Suppose the incidence rate of myocardial...Ch. 7 - Suppose the annual incidence of asthma in the...Ch. 7 - Prob. 18PCh. 7 - Suppose the annual incidence of asthma in the...Ch. 7 - Prob. 20PCh. 7 - Ribosomal 5S RNA can be represented as a sequence...Ch. 7 - Ribosomal 5S RNA can be represented as a sequence...Ch. 7 - Ribosomal 5S RNA can be represented as a sequence...Ch. 7 - Ribosomal 5S RNA can be represented as a sequence...Ch. 7 - Ribosomal 5S RNA can be represented as a sequence...Ch. 7 - Suppose we identify 50 women 50 to 54 years of age...Ch. 7 - The drug erythromycin has been proposed to...Ch. 7 - A pilot study of a new antihypertensive agent is...Ch. 7 - A pilot study of a new antihypertensive agent is...Ch. 7 - The proportion of deaths due to lung cancer in...Ch. 7 - The proportion of deaths due to lung cancer in...Ch. 7 - The proportion of deaths due to lung cancer in...Ch. 7 - The proportion of deaths due to lung cancer in...Ch. 7 - The proportion of deaths due to lung cancer in...Ch. 7 - Iron-deficiency anemia is an important nutritional...Ch. 7 - Iron-deficiency anemia is an important nutritional...Ch. 7 - Iron-deficiency anemia is an important nutritional...Ch. 7 - Iron-deficiency anemia is an important nutritional...Ch. 7 - Iron-deficiency anemia is an important nutritional...Ch. 7 - Iron-deficiency anemia is an important nutritional...Ch. 7 - Iron-deficiency anemia is an important nutritional...Ch. 7 - Iron-deficiency anemia is an important nutritional...Ch. 7 - Suppose a new test is proposed to identify...Ch. 7 - Suppose a new test is proposed to identify...Ch. 7 - Suppose a new test is proposed to identify...Ch. 7 - Suppose a new test is proposed to identify...Ch. 7 - Suppose a new test is proposed to identify...Ch. 7 - The mortality experience of 8146 male employees of...Ch. 7 - The mortality experience of 8146 male employees of...Ch. 7 - The mortality experience of 8146 male employees of...Ch. 7 - The mortality experience of 8146 male employees of...Ch. 7 - Researchers have reported that the incidence rate...Ch. 7 - Researchers have reported that the incidence rate...Ch. 7 - Researchers have reported that the incidence rate...Ch. 7 - Researchers have reported that the incidence rate...Ch. 7 - Left ventricular mass (LVM) is an important risk...Ch. 7 - Left ventricular mass (LVM) is an important risk...Ch. 7 - Left ventricular mass (LVM) is an important risk...Ch. 7 - Left ventricular mass (LVM) is an important risk...Ch. 7 - Prob. 60PCh. 7 - Previous studies have shown that supplementing the...Ch. 7 - Prob. 62PCh. 7 - Prob. 63PCh. 7 - Previous studies have shown that supplementing the...Ch. 7 - Prob. 65PCh. 7 - Prob. 66PCh. 7 - Refer to Data Set NIFED.DAT at...Ch. 7 - The combination of photochemotherapy with oral...Ch. 7 - The combination of photochemotherapy with oral...Ch. 7 - The combination of photochemotherapy with oral...Ch. 7 - Prob. 72PCh. 7 - Breast cancer is strongly influenced by a womans...Ch. 7 - Prob. 74PCh. 7 - An investigator wants to test a new eye drop that...Ch. 7 - Prob. 76PCh. 7 - Table 7.10 gives the itching scores reported by...Ch. 7 - Table 7.10 gives the itching scores reported by...Ch. 7 - Table 7.10 gives the itching scores reported by...Ch. 7 - Table 7.10 gives the itching scores reported by...Ch. 7 - Prob. 81PCh. 7 - Prob. 82PCh. 7 - Concurrent sexual partnerships are widely believed...Ch. 7 - Prob. 84PCh. 7 - Prob. 85PCh. 7 - Prob. 86PCh. 7 - Consider the birthweight data in Example 7.2. What...Ch. 7 - Consider the birthweight data in Example 7.2. Now...Ch. 7 - Prob. 89PCh. 7 - A screening program for neuroblastoma (a type of...Ch. 7 - A screening program for neuroblastoma (a type of...Ch. 7 - Prob. 92PCh. 7 - Prob. 93PCh. 7 - Prob. 94PCh. 7 - Prob. 95PCh. 7 - Prob. 96PCh. 7 - An experiment was performed to assess the efficacy...Ch. 7 - Medical errors are common in hospitals throughout...Ch. 7 - Prob. 99PCh. 7 - Prob. 100PCh. 7 - Prob. 101PCh. 7 - Prob. 102PCh. 7 - Prob. 103PCh. 7 - Prob. 104PCh. 7 - Osteoporosis is an important cause of morbidity in...Ch. 7 - Osteoporosis is an important cause of morbidity in...Ch. 7 - Osteoporosis is an important cause of morbidity in...Ch. 7 - Prob. 108PCh. 7 - Prob. 109PCh. 7 - Prob. 110PCh. 7 - Prob. 111PCh. 7 - Prob. 112PCh. 7 - Prob. 113PCh. 7 - A study was conducted in Sweden to relate the age...Ch. 7 - A study was conducted in Sweden to relate the age...Ch. 7 - A study was conducted in Sweden to relate the age...Ch. 7 - Prob. 117PCh. 7 - Prob. 118PCh. 7 - Prob. 119PCh. 7 - Prob. 120PCh. 7 - Prob. 121P
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