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Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052

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BuyFindarrow_forward

Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052
Chapter 8, Problem 11QP
Textbook Problem
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Polynucleotide chains have a 5′ and a 3′ end. Which groups are found at each of these ends?

  1. a. 5′ sugars, 3′ phosphates
  2. b. 3′ OH, 5′ phosphates
  3. c. 3′ base, 5′ phosphates
  4. d. 5′ base, 3′ OH
  5. e. 5′ phosphates, 3′ bases

Summary Introduction

Introduction: Nucleotides are joined together to form a chain of polynucleotides. Polynucleotides are polar molecules and have different chemical groups at each end.

Explanation of Solution

Reason for correct answer:

The 5 end of DNA is connected with the phosphate group and 3 end contains –OH group. This asymmetry provides direction to the DNA strand.

Option b. is given as “3 OH, 5 phosphates”.

DNA has –OH group at 3 end and a phosphate group at 5 end. Hence, the correct answer is option b.

Reasons for incorrect answer:

Option a. is given as, “5 sugars, 3 phosphates”.

Sugar is a middle component of nucleotides. The phosphate group is attached to one carbon of sugar and the nitrogenous bases are attached to another carbon of sugar ring. At 3 end of DNA –OH group is attached

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