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Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052

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BuyFindarrow_forward

Human Heredity: Principles and Iss...

11th Edition
Michael Cummings
Publisher: Cengage Learning
ISBN: 9781305251052
Chapter 8, Problem 8QP
Textbook Problem
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In analyzing the base composition of a DNA sample, a student loses the information on pyrimidine content. The purine content is A = 27% and G = 23%. Using Chargaff’s rule, reconstruct the missing data and list the base composition of the DNA sample.

Summary Introduction

To determine: The missing data and to list the base composition of the DNA sample.

Introduction: Erwin Chargaff and his team worked on the DNA of different organisms and analyzed the base composition of the DNA. The relationship between purines and pyrimidines can be determined with the help of Chargaff’s rule.

Explanation of Solution

DNA is made up of the sugar-phosphate backbone and nitrogenous bases. These nitrogenous bases are purines and pyrimidines. Purine contains adenine and guanine. However, pyrimidine contains cytosine and thymine. According to the base pair rule, specific purine binds with specific pyrimidines such as A-T and C-G...

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