BIOLOGY: CONCEPTS & INVEST (LL)
4th Edition
ISBN: 9781260505481
Author: Hoefnagels
Publisher: MCG
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Chapter 8, Problem 4MCQ
Summary Introduction
Introduction:
Mutation is a permanent alteration in the
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Which of the following best describes a gene that codes for a tumor-suppressor protein?
a. One that helps to prevent progression through the cell cycle.
b. One that helps prevent apoptosis.
c. One that codes for a DNA repair enzyme.
d. One that supports part of a growth factor signaling pathway.
Which of the following statements correctly describes a characteristic of tumor-suppressor gene?
a) they are frequently overexpressed in cancerous cells.
b) they are cancer-causing genes introduced into cells by viruses.
c) they encode proteins that help prevent uncontrolled cell growth.
d) they often encode proteins that stimulate the cell cycle.
In a wild-type cell, the function of a protein encoded by a tumor-suppressor gene is to cause a cell to ______.
A.) stop dividing
B.)extend its telomeres
C.) grow toward a new blood vessel
D.) respond to a growth factor
Chapter 8 Solutions
BIOLOGY: CONCEPTS & INVEST (LL)
Ch. 8.1 - Explain the roles of mitotic cell division,...Ch. 8.1 - Prob. 2MCCh. 8.2 - Prob. 1MCCh. 8.2 - Prob. 2MCCh. 8.2 - Prob. 3MCCh. 8.2 - Prob. 4MCCh. 8.2 - Prob. 5MCCh. 8.3 - Which cell types divide by binary fission?Ch. 8.3 - Prob. 2MCCh. 8.4 - Prob. 1MC
Ch. 8.4 - Sketch and label the main parts of a duplicated...Ch. 8.5 - Prob. 1MCCh. 8.5 - Prob. 2MCCh. 8.5 - Prob. 3MCCh. 8.5 - Distinguish between mitosis and cytokinesis.Ch. 8.6 - Prob. 1MCCh. 8.6 - Prob. 2MCCh. 8.6 - Prob. 3MCCh. 8.6 - Prob. 4MCCh. 8.6 - List and describe the three most common cancer...Ch. 8.6 - Prob. 6MCCh. 8.6 - Prob. 7MCCh. 8.7 - Prob. 1MCCh. 8.7 - Prob. 2MCCh. 8.8 - Prob. 1MCCh. 8.8 - Prob. 2MCCh. 8 - A DNA molecule is placed in a test tube containing...Ch. 8 - Prob. 2MCQCh. 8 - Prob. 3MCQCh. 8 - Prob. 4MCQCh. 8 - Prob. 5MCQCh. 8 - Prob. 1WIOCh. 8 - Write and explain an analogy for each of these DNA...Ch. 8 - Prob. 3WIOCh. 8 - Obtain a rubber band and twist it as m any times...Ch. 8 - Sketch and describe the events that occur when a...Ch. 8 - Prob. 6WIOCh. 8 - Prob. 7WIOCh. 8 - Describe what will happen to a cell if interphase...Ch. 8 - List the ways that binary fission is similar to...Ch. 8 - Prob. 10WIOCh. 8 - Prob. 11WIOCh. 8 - Why do chemotherapy and radiation sometimes kill...Ch. 8 - Prob. 13WIOCh. 8 - Prob. 1PITCh. 8 - Prob. 2PITCh. 8 - Prob. 3PIT
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- In some cancer cells, a specific gene has been duplicated many times. Is this gene likely to be an oncogene or a tumor-suppressor gene? Explain your reasoningarrow_forwardNormal (nonmutant) tumor-suppressor genes often functiona. as negative regulators of cell division.b. in the maintenance of genome integrity.c. in the stimulation of cell division.d. as both a and b.arrow_forwardCompare and contrast oncogenes and tumor suppressor genes.arrow_forward
- Imagine you have used cBioportal and breast cancer patient datasets and identified a cancer-associated mutation in a particular protein. What would you do next to understand whether that mutation contributes to tumor progression (include experimental approach)?arrow_forwardMuch remains unknown about the rapid, uncontrolled growth, or what causes a tumor to metastasize. Scientists do know that cancer cells come from normal healthy cells that have had some type of damage done to the genes that aid in the production of the regulatory proteins for the cell cycle. What causes this damage? a proto-oncogenes b mutations c enzymes d tumor suppressorsarrow_forwardApart from p53, mention and describe the function of three tumor suppressor genes you knowarrow_forward
- ________ are changes to the nucleotides in a segment of DNA that codes for a protein. a. Proto-oncogenes b. Tumor suppressor genes c. Gene mutations d. Negative regulatorsarrow_forwardSome cancers have been treated with drugs that demethylate DNA.Explain how these drugs might work. Do you think the cancer-causinggenes that responded to the demethylation are likely to have beenoncogenes or tumor-suppressor genes? Explain your reasoning.arrow_forwardThe term differentiation refers to (a) the loss of genes from cells. (b) the acquisition of new functional capabilities by cells. (c) the production of functionally specialized cells. (d) the division of genes among different types of cells.arrow_forward
- Which of the following mutations is MOST likely to cause cancer? A) a mutation that causes a cyclin gene to be expressed at all times during the cell cycle B) a mutation that causes an oncogene to be turned off so that no protein is made C) a mutation that causes a Cdk gene to be turned off so that no protein is made D) a mutation that causes a tumor suppressor gene to be over-expressedarrow_forwardone question with multiple parts! 1A) If you were a cancer biologist interested in developing new drugs that will slow down cancer cell metastasis, which of the following strategies would be most effective? a)Develop an activator of mitosis b)Make Her2 protein that is more active on the surface of the cancer cells c) Develop a molecule that increases telomerase activity d) Gene therapy to add a mutated p53 gene to the cancer cells 1B) You are a genetic counsellor, and a couple comes to you with concerns that if they have a child together the child could have the X-linked recessive disease Duchene muscular dystrophy. The man has the disease whereas the woman is a carrier. Which of the following would be a true statement to tell them? a) 100% of their male offspring will likely be carriers of the recessive allele that causes the disease b) 75% of their female offspring will likely be carriers of the recessive allele that causes the disease c) 100% of their male offspring will likely…arrow_forwardDescribe how the tumor-suppressor genes Rb, p53 and p21 regulate the cell cycle.arrow_forward
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