Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
6th Edition
ISBN: 9780815344322
Author: Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher: W. W. Norton & Company
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Chapter 8, Problem 8P
Summary Introduction

To explain: How is the bigger protein called trypomyosin sediments more slowly than the smaller protein called hemoglobin.

Concept introduction: Sedimentation of one molecule is measured by an analytical ultracentrifugation method that calculates the rate at which the molecules move in response to the centrifugal force created in centrifuge. The sedimentation rate gives the idea about the molecular mass and the size of the molecule. Sedimentation of a particular molecule depends not only on its size but also on its shape. Hemoglobin is a spherical shape protein, and tropomyosin is a rod-shaped protein molecule.

Summary Introduction

To explain: An analogy from every day experience that helps to solve this problem.

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Molecular Techniques: Basic Concepts; Author: Dr. A's Clinical Lab Videos;https://www.youtube.com/watch?v=7HFHZy8h6z0;License: Standard Youtube License