Concept explainers
Interpretation:
The
Concept introduction:
During epoxidation an oxygen atom is transferred to the double bond in alkene with syn stereochemistry. Both C-O bonds are formed o the same face of the double bond. The
The hydroxylation with OsO4 also occurs with syn stereochemistry. The addition of OsO4 to the alkene gives a cyclic osmate which is then cleaved by using aqueous NaHSO3 to yield a cis-1,2-diol.
To state:
The alkene from which the alcohol shown can be prepared. Further to state among the methods, epoxide hydrolysis and OsO4, which can be used to prepare the diol.
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Chapter 8 Solutions
ORGANIC CHEMISTRY-EBOOK>I<
- How to synthesize cis-cyclohexane-1,2-diol from cyclohesanone?arrow_forwardProvide the reagent(s) and the reaction mechanism of the following reaction H₂Narrow_forward47) Provide the structure of the major organic product which results in the following reaction. CH₂ Br KI 48) When 1-iodo-1-methylcyclohexane is treated with NaOCH2CH3, the more highly substituted alkene product predominates. When KOC(CH3)3 is used instead, the less highly substituted alkene product predominates. Offer an explanation.arrow_forward
- The answer choices for part b ["How would you convert the alkene to a epoxide?"] are: (a) Br2/NaNH2 in liq NH3; (b) mCPBA; (c) OsO4Thank you!arrow_forward4. Synthesize the following compound. You may use benzene, acetylene, ethanol and any inorganic reagents. O₂Narrow_forwardWhat is the structure of alkene that, upon ozonolysis reaction, gives only H' ? H. Select one:arrow_forward
- Give the major organic product(s) of the following reaction. HO OMe ? + PCC Meo OMearrow_forwardExplain why pentane-2,4-dione forms two different alkylation products (Aor B) when the number of equivalents of base is increased from one totwo.arrow_forward4. from each. a) Predict the product of the following reactions. Provide the major organic product d) OH 1. TsCl, pyridine 2. H CO₂CH3 Na₂CO3 SHarrow_forward
- what series of synthetic steps could be used to prepare 1-methylcyclohexanol from cyclohexane?arrow_forwardShow how to synthesize 5-nonanone from 1-bromobutane as the only organic starting material.arrow_forwardIf 1-bromopentane is heated in acetone containing NaOH, what is the alkane produced? Draw and explain the step-by-step mechanism of the production of the compoundarrow_forward
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