Concept explainers
Interpretation:
It is to be determined whether the phenoxide ion
Concept introduction:
The strength of a base can be determined on the basis of the pKa value of its conjugate acid. The weaker the conjugate acid, stronger the base. Higher the
An E1 reaction is a two-step mechanism. The first, rate-determining step involves only the substrate. Therefore, the strength of the base does not affect the rate of an E1 reaction. On the other hand, in an E2 reaction, both the substrate and the base are involved in the only (and therefore the rate-determining) step. Since the base initiates the reaction, its strength influences the
A weak base will therefore favor an E1 reaction while a strong base will favor an E2 reaction.
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ORGANIC CHEMISTRY E-BOOK W/SMARTWORK5
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- Show the difference between SN1 and E1 Reactions ?arrow_forwardWhich of the following is not true of the E2 reaction? A bulky base such as tert-butoxide will favor the Hofmann product. concerted mechanism no reactive intermediate Rate = k [R-X] alkyl halide preference: 3o > 2o > 1oarrow_forwardOne of the heptanedione isomers below has a pka of approximately 9 rather than 20. Which isomer? Why? Draw its conjugate base and offer a full explanation of its acidity.arrow_forward
- a. Compound X is benzene, Y is acetic anhydride acid. Complete the following scheme and determine Z! b. Determine which reagents except acetic acid anhydrides can replace Y!arrow_forwardWhat is the rate-determining step for an E1 reaction mechanism?arrow_forwardWhich conditions are optimum for an SN1 reaction?arrow_forward
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