duction of checkpoint proteins so nothing prevents the cells from continually moving forward and reproducing. If a LOF halted the cell cycle but DNA was still replicated, what check point was affected? a) The G1 checkpoint. b) The G2 checkpoint. c) The G0 checkpoint. d) The Metaphase checkpoint.

Biology (MindTap Course List)
11th Edition
ISBN:9781337392938
Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg
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Chapter17: Developmental Genetics
Section: Chapter Questions
Problem 8TYU: Which of the following statements about cancer is false? (a) oncogenes arise from mutations in...
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Dr. Serena Velazquez lands a coveted post-doc position at Johns Hopkins following completion of her MD/PhD in cancer therapeutics to treat late-stage pancreatic cancer using a mouse model. Her post-doc will be devoted to targeted mutagenesis of replicative enzymes to halt cell division in cancerous cells. She reviews mitosis and meiosis before reporting for her first day of work.

 

1)  Cancer is essentially unregulated gene growth. Cancer cells sometimes have LOF mutations that affect the production of checkpoint proteins so nothing prevents the cells from continually moving forward and reproducing. If a LOF halted the cell cycle but DNA was still replicated, what check point was affected?

a)  The G1 checkpoint.
b) The G2 checkpoint.
c) The G0 checkpoint.
d) The Metaphase checkpoint.
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