Match the primary sequence to its characteristics/function/fate 1. mostly hydrophobic, interacts with SRP, cut off v N-signal v signal-anchor 2. hydrophobic, interacts with SRP and translocon, becomes transmembrane helix v stop-anchor 3. found at carboxyl terminus of ER resident proteins, interaction with its receptor directs retrieval from Golgi v nuclear localization sequence 4. hydrophobic, interacts with translocon, becomes transmembrane helix v KDEL 5. basic, interacts with importin-alpha

Match the primary sequence to its characteristics/function/fate 1. mostly hydrophobic, interacts with SRP, cut off v N-signal v signal-anchor 2. hydrophobic, interacts with SRP and translocon, becomes transmembrane helix v stop-anchor 3. found at carboxyl terminus of ER resident proteins, interaction with its receptor directs retrieval from Golgi v nuclear localization sequence 4. hydrophobic, interacts with translocon, becomes transmembrane helix v KDEL 5. basic, interacts with importin-alpha

Biology 2e

2nd Edition

ISBN:9781947172517

Author:Matthew Douglas, Jung Choi, Mary Ann Clark

Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark

Chapter5: Structure And Function Of Plasma Membranes

Section: Chapter Questions

Problem 18RQ: Many viruses enter host cells through receptor- mediated endocytosis, What is an advantage of this...

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Match the primary sequence to its characteristics/function/fate N-signal signal-anchor stop-anchor nuclear localization sequence KDEL 1. found at carboxyl terminus of ER resident proteins, interaction with its receptor directs retrieval from Golgi 2. hydrophobic, interacts with SRP and translocon, becomes transmembrane helix 3. mostly hydrophobic, interacts with SRP, cut off 4. hydrophobic, interacts with translocon, becomes transmembrane helix 5. basic, interacts with importin-alpha
Match the letter in the diagram with the accumulation or localization of active (or about to be active) protein in a given cellular context, which is wild-type unless specified. AD5CES
Which THREE statements are true about targetting proteins to the nudieus? Aln the cytoplasm, a protein with an appropriate nuclear localization signal (NLS)is brund by a compna sd moint Importins a and B and CAS are degraded in the nucieus The nuclear localization sequence usually contains around 20 ameno aoids The nuclear localization sequence contains severai consecutive basic (Arg or Lysi me The nuclear localization sequence is ocated almost anywhere in protein amino aad sequerce The nuclear localization sequence is emoved after targeting to the nucleus
Which of the following small GTP-binding proteins does NOT play a role in cell migration during chemotaxis? O Cap Z Rho Cdc42 O All of the listed GTPases play a role in cell migration O Rac ◆ Previous
anline State- estid%3D1740&strandid%3D&element3D&difficulty=Dassessment&assignment_id%3D42985127&load_test=1&teacherPreview=#test Save Subm gp120 Docking Glycoprotein Lipid Membrane RNA gp41 Transmembrane Glycoprotein Сapsid Matrix Reverse Transcriptase Viruses, although not considered to be alive, attack host cells and cause disease. The attack of a host cell is necessary for the virus to survive for all of the reasons listed EXCEPT one. That is they cannot synthesize proteins becayse they lack ribosomes and must use the ribosomes of their host cells to translate viral messenger RNA into new Eliminate proteins. A) they cannot produce or store energy in the form of ATP and have to get their energy from the host cell. B) they parasitize the host cell for basic molecules like amino acids, nucleotides, and lipids. D) they lack DNA/RNA so they must use the DNA of the host cell. Address 立

What is a plausible mechanism for viral oncoproteins? O Promote the expression of pRb phosphatases O Sequester CDK4/6 disrupting interaction with cyclin D O Sequester pRb disrupting interaction with E2F1 OPhosphorylate p53.
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11 111 FLATRON WIS songs to listen to on a late n (1) Messenger f 253282375 390061782796379 8 x ++ Scontent.fmnl17-4.fna.fbcdn.net/v/t1.15752-9/253282375 390061782796379 8678836692018933574_n.jpg?_nc_cat3D105&ccb%3D1-5&_nc_sid=Dae9488&_nc_eui2=DAeERUdQ E Apps Discussion Questions (answer these questions on a separate sheet of paper) 1. Explain how hCG secretion is regulated. Is it secreted by a pregnant woman or her offspring? 2. hCG depresses some reactions of the immune system. What adaptive advantage do you think this has? Ac P Type here to search LG
6_c. In cancerous cells, CpG islands are: where intercalating agents are found demethylated methylated.
Human immunodeficiency virus (HIV), the causative agent of acquired immune deficiency syndrome (AIDS) infects T-helper cells that have the CD4 receptor on their surface: gp120 CD4 receptor -CXCR4 coreceptor RNA- Revorse transcriptase enzyme Core with - protein coat Capsomeres of protein coat Envelope T cll DNA (a) Structure of HIV (b) HIV infecting a T cell with CD4 receptors, and CXCR4 coreceptors which are distributed over the surface of the cell Copyright e 2001 Benjamin Cummings, an imprint of Addison Wesloy Longman, Inc. A. As shown in the above diagram, HIV attaches to a susceptible cell by a binding interaction between the gp120 protein on the virus protein and the CD4 and CXCR4 receptors on the surface of the T-helper cell. What will be the next event in the virus life cycle? B. One mechanism for transmission of HIV is direct contact during sexual activity. What is the other common mechanism of transmission?
Many viruses enter host cells through receptor- mediated endocytosis, What is an advantage of this entry strategy? The virus directly enters the cytoplasm of the cell The virus is protected from recognition by white blood cells The virus only enters its target host cell type The virus can directly inject its genome into the cell’s nucleus.
What determines the conformation of Mediator? TAND 1 O TAFS 6 and 9 O interactions with transactivator proteins O cyclin H O the phosphorylation state of the CTD