Q9.2: Based on the premise of the thrifty gene hypothesis, predict if the following hypothetical gene variants would be candidate thrifty genes. Explain your answer. Insulin receptor that has an increased affinity for insulin High basal levels of uncoupling protein in liver cells A hyperactive lipoprotein lipase on the plasma membrane in adipose cells

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter17: Metabolism: An Overview
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Problem 8P: How Is Metabolism Regulated? (Integrates with Chapter 15.) Metabolic regulation is achieved via...
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BIOC 385

Metabolic Energy Balance

Q9.2: Based on the premise of the thrifty gene hypothesis, predict if the following hypothetical gene variants would be candidate thrifty genes. Explain your answer.

  1. Insulin receptor that has an increased affinity for insulin
  2. High basal levels of uncoupling protein in liver cells
  3. A hyperactive lipoprotein lipase on the plasma membrane in adipose cells

 

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