structure of its covalent adduct to DNA
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Chlorambucil is a nitrogen mustard. What is the structure of its covalent adduct to DNA?
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- Extrachromosomal DNA is critical to the antibiotic resistance found in microorganisms, how do these DNA elements account for this phenomena?What special kind of nucleotide is used in the Sanger sequencing procedure?What is the name of the enzyme that add nucleotides to a growing DNA strand? What kind of bonds does this enzyme form between the nucleotides?
- Escherichia coli and other bacteria methylate adenines on the original strand to distinguish the original strand from the newly replicated strand of DNA. Why is this distinction important?Why is complimentary base pairing vital to the structure of DNA?What is the difference between a deoxynucleotide triphosphate (dNTP) and a dideoxynucleotide triphosphate (ddNTP)?