The physical foundation of sickle cell disease is caused by a hemoglobin mutation that is prone to polymerization as a consequence of a surface-exposed valine residue on the hemoglobin molecule. if it is true or untrue
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Q: Using sickle-cell anemia as an example, describe what is meant by a molecular or genetic disease.…
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The physical foundation of sickle cell disease is caused by a hemoglobin mutation that is prone to
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- Using sickle-cell anemia as an example, describe what is meant by a molecular or genetic disease. What are the similarities and dissimilarities between this type of a disorder and a disease caused by an invading microorganism?Adenosine triphosphate is an imortant molecule becauseitWhat other possible organizations of the globin gene could exist if there were no need for a globin chaperone?
- What is the difference between sickle-cell amino acid sequence and normal amino acid sequence?Sickle-Cell Anemia is one disease that arises from a known point mutation in a protein. This statement is: True FalseWhich of the given disorder can be seen in an individual when the mutation includes substitution of a purine by pyrimidine? 1. Chronic myelogenous leukemia 2. Sickle cell anaemia 3. a thalassemia 4. B thalassemia
- Sickle cell anemia is caused by a point mutation in the β-globin chain of hemoglobin. Glutamic acid is replaced by Valine. HBB sequence in normal adult hemoglobin (Hb A): Leu-Thr-Pro-Glu-Glu-Lys-Ser HBB sequence in mutant adult hemoglobin (Hb S): Leu-Thr-Pro-Val-Glu-Lys-Ser What effect does this mutation have on the structure and function of the protein? Predict what would happen to the RBC if the glutamic acid was replaced with asparagine instead of valine.Considering that we are all made up of the same 4 nucleotides in our DNA, the same 4 nucleotides in our RNA, and the same 20 amino acids in our proteins, why are we so different from each other? For example, why do some people have sickle cell anemia and others don't?Why does Valerie's blood from her peripheral, tumor and breast samples all show bands of DNA that are 3000 bases and 1282 bases long?
- Why might the locations of introns and exons be the same in both alpha- and beta-hemoglobin genes?Can you please briefly define these five classes of domain folds.: α, β, α / β, α + β, and cross-linked domains, and compare/contrast the four helix-bundle and the globin fold?Define the term adenosine triphosphate?
