Which of the following would most likely mimic Rb loss? Rb mutant where the phosphosites are mutated to alanine G1 cyclin with a shorter half-life Constitutively active E2F Ras GTPase mutant with increased hydrolysis activity

Which of the following would most likely mimic Rb loss? Rb mutant where the phosphosites are mutated to alanine G1 cyclin with a shorter half-life Constitutively active E2F Ras GTPase mutant with increased hydrolysis activity

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter32: The Reception And Transmission Of Extracellular Information

Section: Chapter Questions

Problem 21P

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Question

please help

Which of the following would most likely mimic Rb loss?
Rb mutant where the phosphosites are mutated to alanine
G1 cyclin with a shorter half-life
Constitutively active E2F
Ras GTPase mutant with increased hydrolysis activity
Loss of Ras-GEF

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