Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 11, Problem 5PDQ
Predict the results of the experiment by Taylor, Woods, and Hughes if replication were (a) conservative and (b) dispersive.
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Describe the Meselon -Stahl experiment Include how they distinguished new from old DNA strands, what the centrifuge was for, and how it showed semi-conservative replication.
If DNA replication were dispersive instead of semi-conservative how many "bands" would Meselson and Stahl have expected to see in their experiment after 4 rounds of replication in "light" nucleotides?
How did the results prove the semiconservative model of DNA replication? Explain
Chapter 11 Solutions
Concepts of Genetics (12th Edition)
Ch. 11 - In the Meselson-Stahl experiment, which of the...Ch. 11 - An alien organism was investigated. When DNA...Ch. 11 - Why might mutations in genes encoding telomerase...Ch. 11 - Although the brother is an immunologically matched...Ch. 11 - Prob. 3CSCh. 11 - HOW DOWE KNOW? In this chapter, we focused on how...Ch. 11 - CONCEPT QUESTION Review the Chapter Concepts list...Ch. 11 - Compare conservative, semiconservative, and...Ch. 11 - Describe the role of 15N in the MeselsonStahl...Ch. 11 - Predict the results of the experiment by Taylor,...
Ch. 11 - What are the requirements for in vitro synthesis...Ch. 11 - In Kornbergs initial experiments, it was rumored...Ch. 11 - How did Kornberg assess the fidelity of DNA...Ch. 11 - Which characteristics of DNA polymerase I raised...Ch. 11 - Kornberg showed that nucleotides are added to the...Ch. 11 - What was the significance of the polA1 mutation?Ch. 11 - Summarize and compare the properties of DNA...Ch. 11 - List and describe the function of the ten subunits...Ch. 11 - Distinguish between (a) unidirectional and...Ch. 11 - List the proteins that unwind DNA during in vivo...Ch. 11 - Define and indicate the significance of (a)...Ch. 11 - Outline the current model for DNA synthesis.Ch. 11 - Why is DNA synthesis expected to be more complex...Ch. 11 - Suppose that E. coli synthesizes DNA at a rate of...Ch. 11 - Several temperature-sensitive mutant strains of E....Ch. 11 - While many commonly used antibiotics interfere...Ch. 11 - Describe the end-replication problem in...Ch. 11 - Many of the gene products involved in DNA...Ch. 11 - In 1994, telomerase activity was discovered in...Ch. 11 - The genome of D. melanogaster consists of...Ch. 11 - Prob. 26ESPCh. 11 - DNA polymerases in all organisms add only 5...Ch. 11 - Assume that the sequence of bases shown below is...Ch. 11 - Reiji and Tuneko Okazaki conducted a now classic...Ch. 11 - Consider the drawing of a dinucleotide below. (a)...Ch. 11 - To gauge the fidelity of DNA synthesis, Arthur...
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- Briefly describe how the use of different nitrogen isotopes allowed Meselson and Stahl to discern that DNA replication is semi-conservative.arrow_forwardWhat would Meselson and Stahl have seen after 1,2, and 3 generations of replication if the dispersive model of DNA replication were correct?arrow_forwardCite evidence from Meselson and Stahl’s experiment that enabled scientists to differentiate between semiconservative replication of DNA and alternative models.arrow_forward
- If DNA replication followed the dispersive model of replication, how would the outcomes of the Meselson-Stahl experiment change? Describe the composition of DNA samples after one and two rounds of replication, and how this is different from the findings of the original experiment.arrow_forwardIn the Meselson–Stahl experiment thatestablished the semiconservative nature of DNA replication,the extraction method produced short fragments of DNA. Whatsort of results might have been obtained with longer piecesof DNA?arrow_forwardExplai why the Meselson and Stahl experiment requires two rounds of replication. Draw a diagram.arrow_forward
- Describe at least three proof-reading mechanisms to achieve High Fidelity of DNA replication.arrow_forwardWhich property of DNA double helix led Watson and Crick to hypothesisesemi-conservative mode of DNA replication? Explain.arrow_forwardWhy were Meselson and Stahl unable to distinguish between the dispersive and the semiconservative models following only one round of DNA replication?arrow_forward
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