Principles of Biology
2nd Edition
ISBN: 9781259875120
Author: Robert Brooker, Eric P. Widmaier Dr., Linda Graham Dr. Ph.D., Peter Stiling Dr. Ph.D.
Publisher: McGraw-Hill Education
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Chapter 11.2, Problem 1BC
Summary Introduction
To explain:
The reason due to which DNA polymerase cannot copy the 3’ end of a linear chromosome.
Introduction:
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Describe the steps of DNA replication. (3 sentences please)
The diagram depicts one strand of DNA at the end of a chromosome. This strand has been replicated and produced two fragments, as shown below. Which of the two gaps that exist, labeled (a) and (b), can be filled by DNA polymerase? Hint: remember the directionality requirement for DNA polymerase.
a) gap (a)
b) gap (b)
c) both gaps (a) and (b)
d) neither gaps (a) nor (b)
b) Discuss the characteristic of DNA polymerase 1,
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Chapter 11 Solutions
Principles of Biology
Ch. 11.1 - Which of these binding interactions might be...Ch. 11.1 - Prob. 1TYKCh. 11.1 - When an ncRNA functions as a decoy, it contains...Ch. 11.2 - Prob. 1BCCh. 11.2 - Prob. 1CCCh. 11.2 - Prob. 1TYKCh. 11.3 - Prob. 1CCCh. 11.3 - Prob. 1TYKCh. 11.4 - Explain why RISC binds to a specific mRNA. What...Ch. 11.4 - The process of RNA interference may lead to the...
Ch. 11.4 - To catalyze the methylation of an rRNA, a snoRNA...Ch. 11.5 - Prob. 1BCCh. 11.5 - Prob. 1TYKCh. 11.6 - Prob. 1CCCh. 11.6 - Which of the following components are needed for...Ch. 11.6 - Prob. 2TYKCh. 11.7 - Prob. 1TYKCh. 11 - Which of the following types of molecules could...Ch. 11 - Prob. 2TYCh. 11 - Prob. 3TYCh. 11 - Prob. 4TYCh. 11 - Prob. 5TYCh. 11 - Prob. 6TYCh. 11 - Prob. 7TYCh. 11 - Prob. 8TYCh. 11 - Prob. 9TYCh. 11 - Prob. 10TYCh. 11 - An ncRNA may have the following funtions:...Ch. 11 - Prob. 2CCQCh. 11 - Prob. 3CCQCh. 11 - Review the concept of an RNA world described in...Ch. 11 - Prob. 2CBQ
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- Figure 14.14 You isolate a cell strain in which the joining of Okazaki fragments is impaired and suspect that a mutation has occurred in an enzyme found at the replication fork. Which enzyme is most likely to be mutated?arrow_forwardDiscuss Concepts A forensic scientist obtained a small DNA sample from a crime scene. In order to examine the sample, he increased its quantity by cycling the sample through the polymerase chain reaction. He estimated that there were 50,000 copies of the DNA in his original sample. Derive a simple formula and calculate the number of copies he will have after15 cycles of the PCR.arrow_forwardA chromosome contains many different genes that are transcribed into different ___ . a. proteins b. polypeptides c. RNAs d. a and barrow_forward
- C. Why does isolated DNA appear stringy?arrow_forward(a) What is the function of helicase in DNA replication?(b) What is the function of DNA polymerase?(c) What are replication forks? Compare and contrast leading and lagging strands. Answer all pleasearrow_forwardSelect the characteristics/descriptions of DNA polymerase. Select ALL that apply requires a primer adds nucleotides to 3' end of DNA strand adds nucleotides to 5' end of DNA strand does not require primer has 3'-to-5' exonuclease activity that allows "proofreading" of DNA strand being madearrow_forward
- Consider the following segment of DNA, which is part of a linear chromosome: LEFT 5’.…TGACTGACAGTC….3’ 3’.…ACTGACTGTCAG….5’ RIGHT During DNA replication, this double-strand molecule is separated from the right to the left into two single strands and the replisome is moving from the right to the left of the segment. The replisome is approaching to a chromosomal end on the left. Considering this left chromosomal end, if without telomerase, the newly synthesized daughter DNA of ___________ will be shortened? neither top or bottom strand both top and bottom strands the top strand the bottom strandarrow_forwardDescribe the role of the proteins involved with DNA replication. Also identify if the protein is involved the leading strand, lagging strand or both. DNA Ligase DNA Polymerase I DNA Polymerase III Helicase Primase Single-stranded DNA-binding proteins Topoisomerasearrow_forwardGive 2 advantages of SPACER DNA SEQUENCES as regions in the genome/chromosome totarget for DNA marker development.arrow_forward
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