Principles of Biology
2nd Edition
ISBN: 9781259875120
Author: Robert Brooker, Eric P. Widmaier Dr., Linda Graham Dr. Ph.D., Peter Stiling Dr. Ph.D.
Publisher: McGraw-Hill Education
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Chapter 11.2, Problem 1TYK
Summary Introduction
Introduction:
Telomerase is ribonucleoprotein that adds specific telomere repeats sequences to the 3’ end of telomeres. Telomerase is also known as a terminal transferase. The telomere is the area of repetitive sequences present at the end of most eukaryotes. The main function of telomere is to protect the end of the chromosomes from damage.
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To synthesize DNA, what does telomerase use as a template?
a. It uses the DNA in the 3′ overhang region.
b. It uses RNA that is a component of telomerase.
c. No template is used.
d. Both a and b are correct.
Which of the following are unique to RNA polymerase and not found in RDRP? (In other words not shared between the two. Select all that apply.)
a) Double-stranded template
b) DNA template
c) NTP input
d) RNA product
All of the following statements about telomerase are correct except:
A. the RNA component acts as a template for the synthesis of a segment of DNA.
B. it adds telomeric repeats to the 5'-ends of the DNA strands.
C. it provides a mechanism for replicating the ends of linear chromosomes.
D. it recognizes a G-rich single strand of DNA
E. it is a reverse transcripcase.
Chapter 11 Solutions
Principles of Biology
Ch. 11.1 - Which of these binding interactions might be...Ch. 11.1 - Prob. 1TYKCh. 11.1 - When an ncRNA functions as a decoy, it contains...Ch. 11.2 - Prob. 1BCCh. 11.2 - Prob. 1CCCh. 11.2 - Prob. 1TYKCh. 11.3 - Prob. 1CCCh. 11.3 - Prob. 1TYKCh. 11.4 - Explain why RISC binds to a specific mRNA. What...Ch. 11.4 - The process of RNA interference may lead to the...
Ch. 11.4 - To catalyze the methylation of an rRNA, a snoRNA...Ch. 11.5 - Prob. 1BCCh. 11.5 - Prob. 1TYKCh. 11.6 - Prob. 1CCCh. 11.6 - Which of the following components are needed for...Ch. 11.6 - Prob. 2TYKCh. 11.7 - Prob. 1TYKCh. 11 - Which of the following types of molecules could...Ch. 11 - Prob. 2TYCh. 11 - Prob. 3TYCh. 11 - Prob. 4TYCh. 11 - Prob. 5TYCh. 11 - Prob. 6TYCh. 11 - Prob. 7TYCh. 11 - Prob. 8TYCh. 11 - Prob. 9TYCh. 11 - Prob. 10TYCh. 11 - An ncRNA may have the following funtions:...Ch. 11 - Prob. 2CCQCh. 11 - Prob. 3CCQCh. 11 - Review the concept of an RNA world described in...Ch. 11 - Prob. 2CBQ
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- The restriction endonucleases used in recombinant DNA work: a. are synthesized by bacteria b. recognize sequences 14-16 bp long c. cut the DNA outside the recognition sequence d. all the above are truearrow_forwardA cloned fragment of DNA was sequenced by using thedideoxy chain-termination method. A part of the autoradiogram of the sequencing gel is represented here.ddA ddG ddT ddCa. Deduce the nucleotide sequence of the DNAnucleotide chain synthesized from the primer. Label the5′ and 3′ ends.b. Deduce the nucleotide sequence of the DNAnucleotide chain used as the template strand. Label the5′ and 3′ ends.c. Write out the nucleotide sequence of the DNA doublehelix (label the 5′ and 3′ ends)arrow_forwardWhich is the odd one out ? For the rest, explain the concept/process/technique they are involved with. polymerase primers DNA RNA topoisomerasearrow_forward
- Below is a template strand (top) being replicated by DNA polymerase. The black arrow is pointing to: 3' end OR 5' end? The extra T in one of the strands resulted from DNA polymerase slipping: forward OR backward and could lead to a deletion mutation OR an insertion mutation if not repaired.arrow_forwardWhich of the following matches is not correct? a. Template = Double stranded DNA b. Primer = short fragment of RNA c. Synthesis of the new DNA = template strand read in the 3' to 5' direction d. All of the above choices are incorrectarrow_forwardDraw a figure showing annealing and extension of the oligos to form the DNA template.Label the following parts on your diagram: T7 Promoter, GG, Target Sequence, Tail Overlap, Tail. Explain the purpose of each labeled partarrow_forward
- The activity of restriction enzymes may produce fragments with sticky ends. Sticky ends are a) a type of endonucleases. b) dephosphorylated CpG islands. c) unpaired nucleotides. d) double breaks with blunt ends.arrow_forwardLinear chromosomes would shorten after each DNA replication because the gaps created by the removal of primers are not filled. Telomerase is an enzyme that fills this gap using an RNA template (a conceptual diagram of the function is shown below; actually this is a protein-RNA complex). Most human cells do not have the telomerase activity and thus can divide only a limited number of times. _________ exceptionally have telomerase activity because these cells are supposed to pass the complete DNA to the next generation. By Sierra Sciences, LLC - Sierra Sciences, LLC (uploaded from intranet), CC BY 3.0, https://commons.wikimedia.org/w/index.php?curid=7988056 Brain cells Germline cells Cancer cells Hepatic cellsarrow_forwardWhat occurs during the HIGH temperature step of PCR? A) DNA is cut by restriction endonucleases B) primers get degraded C) primers anneal to single-stranded DNA D) DNA is synthesized E) double stranded DNA separates into single stranded DNAarrow_forward
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