Biological Science (7th Edition)
7th Edition
ISBN: 9780134678320
Author: Scott Freeman, Kim Quillin, Lizabeth Allison, Michael Black, Greg Podgorski, Emily Taylor, Jeff Carmichael
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Concept explainers
Question
Chapter 12, Problem 9TYPSS
Summary Introduction
Introduction:
Interphase and metaphase are the two phases of the cell cycle. In interphase, the cell prepares itself for its division, while during metaphase the cell matures its genetic material for replication.
Expert Solution & Answer
![Check Mark](/static/check-mark.png)
Want to see the full answer?
Check out a sample textbook solution![Blurred answer](/static/blurred-answer.jpg)
Students have asked these similar questions
The following diagram indicates how the cell cycle progresses in typical human cells:
INTERPHASE
G₁
MITOTIC
(M) PHASE
Mitosis
Cytokinesis
DRUG
S
(DNA synthesis)
G2
Suppose that you are investigating potential drugs that might be used to stop the out of control growth
of tumor cells. The following table lists several experimental drugs along with some information about
their effect on cells. Predict which stage of the cell cycle might be inhibited by each of the drugs (A
through E).
COMMENTS
Shown to block the
You are studying a new fungus, G. lucasus, and are interested the molecules that control the cell cycle of this new organism. You make some mutant cells and find an intriguing mutant that
has two mutations - one in the force gene and one in the darkside gene.
a. You perform propidium-iodide cell cycle analysis by flow cytometry on wild-type and the double mutant cells and your results are below. During what stage(s) of the cell cycle are the
double mutant cells arresting their growth? Please briefly explain your answer.
# of cells
Wild-Type Cells
In
180 kDa
110 kDa
80 kDa
b. In studying the gene products of the force and darkside genes, you determine that the force gene produces a polypeptide of 80 kDa, and the darkside gene produces a polypeptide of 42
kDa. You collect lysates from wild-type cells in G₁, S, or G₂/M phases of the cell cycle and perform a Western blot (immunoblot) with either an antibody against force or an antibody against
darkside ... only you forget to label your…
Looking at the the time intervals in the figure given, compare the time spent in mitosis with the time spent in gap1 in human liver cells.
A. less time is spent in G1 than in M
B. a little more time is spent in G1 than in M
C. The cell spends 10 hours less in G1 than it does in M
D. The cell spends 10 hours more in G1 than it does in M
Chapter 12 Solutions
Biological Science (7th Edition)
Ch. 12 - 1. Which statement about the daughter cells...Ch. 12 - After S phase, what comprises a single chromosome?...Ch. 12 - Progression through the cell cycle is regulated by...Ch. 12 - 4. What major events occur during anaphase of...Ch. 12 - 5. Identify at least two events in the cell cycle...Ch. 12 - 6. What evidence suggests that during anaphase,...Ch. 12 - 7. Evaluate each of the following defects. Which...Ch. 12 - Prob. 8TYUCh. 12 - Prob. 9TYPSSCh. 12 - Prob. 10TYPSS
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Cancer stem cells (CSCs) are cancer cells (found within tumors or hematological cancers) that possess characteristics associated with normal stem cells, specifically the ability to give rise to all cell types found in a particular cancer sample. There are many biomedical engineering based approaches to detect CSCs. Question: What is the importance and advanatge of detecting CSCs?arrow_forwardWhich of the following is true of normal adult cells but NOT cancer cells? A. Cell death after a finite number of cell divisions B. Contact with other cells increases likelihood of division C. Large amount of telomerase present D. Do not care about cell density while culturearrow_forwardFor most cell types, serum must be added to the media to get cells to grow and proliferate in culture. Nevertheless, serum is very expensive and can complicate experiments utilizing the cells. Many companies have developed "artificial serum" which enables cells to multiply without the use of serum. See data below. What are likely components of the artificial serum that enables cells to grow. Explain (limit 3-4sentences). Non 2% Human plasma 1% Artificial serum(XF) 1% Artificial serum(AF) 104 cells/cm² Cell density cultured after 4 days 127 10- 2 0 NON 2% 1% 1% Human Artificial Artificial plasma serum(XF) serum(AF) PDL [times] 30- 25+ 20- 15- 10- 5- 0 -2% Human plasma 0 Subculture 1% Artificial serum (XF) 1% Artificial serum(AF) 5 10 15 20 25 30 Culture days Medium: HFDM-1 (+) was used.arrow_forward
- Cancer stem cells (CSCs) are cancer cells (found within tumors or hematological cancers) that possess characteristics associated with normal stem cells, specifically the ability to give rise to all cell types found in a particular cancer sample. There are many biomedical engineering based approaches to detect CSCs. Question: What is the importance and advanatge of detecting Cancer stem cells (CSCs)? Please explain in details with your own words. Thank you.arrow_forwardCancer stem cells (CSCs) are cancer cells (found within tumors or hematological cancers) that possess characteristics associated with normal stem cells, specifically the ability to give rise to all cell types found in a particular cancer sample. There are many biomedical engineering based approaches to detect CSCs. Question: What is the importance and advanatge of detecting CSCs? Make a list of it.arrow_forwardExplain the following figure. According to this model, what are the two major phases of metastasis that must be successful for metastasis? What are the challenges faced by cancer cells during metastatizing?arrow_forward
- Cancer stem cells (CSCs) are cancer cells (found within tumors or hematological cancers) that possess characteristics associated with normal stem cells, specifically the ability to give rise to all cell types found in a particular cancer sample. There are many biomedical engineering based approaches to detect CSCs. Question: What is the importance and advanatge of detecting CSCs? Please explain in detail the main findings with your own words.arrow_forwardCancer stem cells (CSCs) are cancer cells (found within tumors or hematological cancers) that possess characteristics associated with normal stem cells, specifically the ability to give rise to all cell types found in a particular cancer sample. There are many biomedical engineering based approaches to detect CSCs. Question: What is the importance and advanatge of detecting CSCs? Please explain in detailarrow_forwardCancer stem cells (CSCs) are cancer cells (found within tumors or hematological cancers) that possess characteristics associated with normal stem cells, specifically the ability to give rise to all cell types found in a particular cancer sample. There are many biomedical engineering based approaches to detect CSCs. Question: What kind of systems have been developed to detect CSCs? Describe by giving examples. Thank you.arrow_forward
- Vinblastine is a standard chemotherapeutic drug used to treat cancer. Because it interferes with the assembly of microtubules, its effectiveness must be related to Select one: a. inhibition of DNA synthesis. O b. myosin denaturation and inhibition of cleavage furrow formation. c. suppression of cyclin production. Od. inhibition of regulatory protein phosphorylation. O e. disruption of mitotic spindle formation. Next pagearrow_forwardCancer stem cells (CSCs) are cancer cells (found within tumors or hematological cancers) that possess characteristics associated with normal stem cells, specifically the ability to give rise to all cell types found in a particular cancer sample. There are many biomedical engineering based approaches to detect CSCs. Question: What is the importance and advantages of detecting CSCs? Make a list of it. Thank you.arrow_forwardCellular reprogramming and induced pluripotent stem cells have allowed scientists to model various diseases and screen drugs in these in vitro models. Cancer is modeled through the generation of induced pluripotent stem cells. Please explain the questions in detail (Especially 2nd and 3rd question please, thank you):1) why is it important to model such a disease(cancer)?2) what were the key findings after modeling such a disease (cancer)? 3) a drug that has been screened in this disease model (cancer). Explain in detail the main findings.arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education
![Text book image](https://www.bartleby.com/isbn_cover_images/9780134580999/9780134580999_smallCoverImage.gif)
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
![Text book image](https://www.bartleby.com/isbn_cover_images/9781947172517/9781947172517_coverImage_Textbooks.gif)
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
![Text book image](https://www.bartleby.com/isbn_cover_images/9781259398629/9781259398629_smallCoverImage.gif)
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
![Text book image](https://www.bartleby.com/isbn_cover_images/9780815344322/9780815344322_smallCoverImage.gif)
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
![Text book image](https://www.bartleby.com/isbn_cover_images/9781260159363/9781260159363_smallCoverImage.gif)
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
![Text book image](https://www.bartleby.com/isbn_cover_images/9781260231700/9781260231700_smallCoverImage.gif)
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education
An Introduction to the Human Genome | HMX Genetics; Author: Harvard University;https://www.youtube.com/watch?v=jEJp7B6u_dY;License: Standard Youtube License