Biological Science (7th Edition)
7th Edition
ISBN: 9780134678320
Author: Scott Freeman, Kim Quillin, Lizabeth Allison, Michael Black, Greg Podgorski, Emily Taylor, Jeff Carmichael
Publisher: PEARSON
expand_more
expand_more
format_list_bulleted
Concept explainers
Question
Chapter 12, Problem 8TYU
Summary Introduction
To review:
Compare and contrast the effects of removing growth factors from asynchronous cultures of human cells that are normal and those that are cancerous.
Introduction:
A normal cell will undergo all the phases of the cell cycle, that is, two gap phases (G1 and G2), synthesis phase (S), and mitosis phase (M) in a controlled manner. While cancerous cells undergo the cell cycle in an uncontrolled manner. Growth factors are proteins required for the growth in the living cells. Asynchronous cultures or cell cultures contain cells that are all in the different growth stages.
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
Can the proteomic fingerprint help determine if a given cancer is resistant or sensitive to a particular chemotherapeutic drug?
name any two methods that can possibly cure cancer .
Personalized cancer treatments involve identifying specific pathways in an individual tumor and selecting drugs that are effective for the modified pathways. One way to do this is to take culture cells from a biopsy of a specific paient and test the effects of a battery of drugs on the patiets cells in culture. How might heterotypic interactions complicate this strategy? How might cells be cultured differently to minimize these complications (limit 5-6 sentences)?
Chapter 12 Solutions
Biological Science (7th Edition)
Ch. 12 - 1. Which statement about the daughter cells...Ch. 12 - After S phase, what comprises a single chromosome?...Ch. 12 - Progression through the cell cycle is regulated by...Ch. 12 - 4. What major events occur during anaphase of...Ch. 12 - 5. Identify at least two events in the cell cycle...Ch. 12 - 6. What evidence suggests that during anaphase,...Ch. 12 - 7. Evaluate each of the following defects. Which...Ch. 12 - Prob. 8TYUCh. 12 - Prob. 9TYPSSCh. 12 - Prob. 10TYPSS
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Why is it important to model cancer through the generation of induced pluripotent stem cells ? Please list item by item. Explain in detail the main findings.arrow_forwardWhy is it important to model cancer through the generation of induced pluripotent stem cells ? Explain in detail the main findings. Please sort as a list.arrow_forwardWhat technique is used to identify genes involved in cancer formation ?arrow_forward
- Please select correct onearrow_forwardTissues and differentiation a)Explain what is meant by termination and differentiation ).b) Explain the difference between an oncogenic and a tumour suppressor gene and describe how they are involved in the onset of cancerarrow_forwardThe following are drugs that act as anti-tumor agents and are often used as part ofchemotherapeutic regimens for cancer patients. Explain how the use of the following drugs mayprevent cancer cell growth and/or proliferation.arrow_forward
- Discuss why certain cell types are less likely and others are more likely to develop cancer than others.arrow_forwardWhich of the following is true of tumor suppressor genes? Group of answer choices a) If this gene is overactive, it becomes an oncogene b) If one of the alleles is mutated, there is usually little effect. Two inactivating mutations are usually required for loss of function (recessive mutation). c) If one copy is lost, the gene no longer functions (dominant mutation) d) Tumor suppressors genes usually cause mitosis or cell growth e) Tumor suppressor genes decrease apoptosisarrow_forwardHeterotypic interactions of tumor cells have been a fertile area for potential therapeutic interventions. Find a specific example of a drug/therapy that targets these interactions and explain the mechanism by which it treats cancer.arrow_forward
- Describe how radiation therapy,chemotherapy, and surgery may all be usedto treat cancer.arrow_forwardWhy is it important to model cancer through the generation of induced pluripotent stem cells ? Explain in detail the main findings.arrow_forwardA microarray is a technique used to develop a profile of the messenger RNA being transcribed by cells at a particular point in the life cycle of the cell. This allows the researcher to detect the expression of particular genes at a particular time. Microarrays have proven very useful in the detection of genes involved in certain types of cancer. If the product of a particular gene functions as a tumor suppressor, which piece of evidence do you think would be the most useful in the diagnosis of a cancer due to a nonsense mutation in this tumor-suppressor gene? (Hint: Don't worry about what a microarray is. Think about what you know about mitosis, cancer, and types of mutation.) O The tissue sample responds to treatment with a mitosis-promoting compound. O The tissue sample shows a high level of gene expression relative to a control (noncancerous) sample. O The mRNAs for the targeted tumor suppressor sequence are not being produced. O The mRNAs for cyclins and kinases show unusually high…arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Concepts of BiologyBiologyISBN:9781938168116Author:Samantha Fowler, Rebecca Roush, James WisePublisher:OpenStax CollegeHuman Biology (MindTap Course List)BiologyISBN:9781305112100Author:Cecie Starr, Beverly McMillanPublisher:Cengage LearningHuman Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning
Concepts of Biology
Biology
ISBN:9781938168116
Author:Samantha Fowler, Rebecca Roush, James Wise
Publisher:OpenStax College
Human Biology (MindTap Course List)
Biology
ISBN:9781305112100
Author:Cecie Starr, Beverly McMillan
Publisher:Cengage Learning
Human Heredity: Principles and Issues (MindTap Co...
Biology
ISBN:9781305251052
Author:Michael Cummings
Publisher:Cengage Learning
An Introduction to the Human Genome | HMX Genetics; Author: Harvard University;https://www.youtube.com/watch?v=jEJp7B6u_dY;License: Standard Youtube License